International Perfusion Association

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IPA

Category: Pediatric

Impact of Pre-Bypass Ultrafiltration on Prime Values and Clinical Outcomes in Neonatal and Infant Cardiopulmonary Bypass

Pre-bypass Ultrafiltration (PBUF) was found to standardize and make more physiologic the values for electrolytes, glucose, and lactate in blood primes used for cardiopulmonary bypass in congenital cardiac surgery, without significantly affecting in-hospital outcomes. This retrospective study compared patients ≤ 1 year old undergoing cardiac surgery with PBUF to those without, showing significant improvements in the physiologic values of PBUF-treated circuits.

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December 21, 2023

An in vitro Comparison of Intra-Operative Isohemagglutinin and Human Leukocyte Antigen Removal Techniques in Pediatric Heart Transplantation

This study compared two plasmapheresis techniques, membrane-based (MP) and centrifuge-based (CP), for their effectiveness in reducing isohemagglutinin titers (IT) and human leukocyte antigen (HLA) antibodies in highly sensitized pediatric patients awaiting heart transplants. Both methods, incorporated into extracorporeal circuits, effectively reduced circulating antibodies, with CP showing slightly greater efficiency in reducing ITs and anti-HLA class II antibody mean fluorescence intensity, although further in vivo studies are needed for confirmation.

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December 21, 2023
Pediatric ECPR

ECPR for Prolonged Pediatric Cardiac Arrest, an Autcome Without Major Neurological Compromise

Pediatric in-hospital cardiac arrest (IHCA) occurs in 1-6% of pediatric ICU admissions, with survival rates improving from 9% to 35% over the past 25 years, partly due to the use of ECMO as a rescue strategy. A case is reported of a 4-month-old patient with ventricular and septal defects who underwent surgery, experienced complications leading to a prolonged cardiac arrest, and was successfully treated with ECMO.

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December 21, 2023
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