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Heart to Heart Mission

For more than 20 years, the IPA has performed life-saving heart surgery on over 400 patients in Santiago, Dominican Republic.

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Honduras Mission

The IPA is working with Duke to expand their heart surgery mission program in Honduras. We have a mission trip planned for mid-May. Stay tuned for more information.

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Your Mission Trip

The IPA will gladly make donations to qualified charitable organizations who perform cardiac surgery mission work for patients in need.

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600+

Patients served

Help Mend a Heart!

Every member of our team is an unpaid volunteer, so please take comfort in knowing that 100% of all donated funds go directly to patient care. Your generosity is so very welcome and will help save lives!
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— Latest News —

Perioperative Bleeding Is Not an Independent Risk Factor for Acute Kidney Injury

Perioperative Bleeding Is Not an Independent Risk Factor for Acute Kidney Injury in On-pump Cardiac Surgery—A Post-hoc Analysis of a Randomized Clinical Trial

A post-hoc analysis of the ALBICS randomized trial with 1,386 cardiac surgery patients found that perioperative bleeding, as classified by the Universal Definition of Perioperative Bleeding (UDPB), was not independently linked to acute kidney injury (AKI). Rather, bleeding indirectly contributed to AKI through hypotension and fluid overload. The only transfusion product independently associated with AKI was fresh frozen plasma.

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April 1, 2025
A Clinical Comparison of the Effects of Six Disposable Cardiopulmonary Bypass Circuits on Bleeding and Coagulation: A Quality Assurance Project

A Clinical Comparison of the Effects of Six Disposable Cardiopulmonary Bypass Circuits on Bleeding and Coagulation: A Quality Assurance Project

This study compared six Health Canada-approved cardiopulmonary bypass (CPB) circuits in 872 cardiac surgery patients to assess their effects on bleeding and coagulation. While all circuits impaired coagulation, significant differences in bleeding severity and transfusion requirements were found after adjusting for patient and procedural factors. Circuit 6 showed the best performance in minimizing transfusion needs.

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March 30, 2025
Cerebral Inflammation in an Animal Ischemia

Cerebral Inflammation in an Animal Ischemia–Reperfusion Model Comparing Histidine-Tryptophan–Ketoglutarate and Del Nido Cardioplegia

This study compares two cardioplegic solutions—HTK and Del Nido—for their impact on cerebral inflammation in a porcine cardiopulmonary bypass model. Results showed that while both solutions produced comparable hypoxia and inflammation markers overall, HTK led to more pronounced hyponatremia, hypochloremia, and increased IL-1β mRNA in certain brain regions. Del Nido cardioplegia provided more stable electrolyte levels and less cerebral inflammation.

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March 30, 2025
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Help Mend a Heart!

Every member of our team is an unpaid volunteer, so please take comfort in knowing that 100% of all donated funds go directly to patient care. Your generosity is so very welcome and will help save lives!
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