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Heart to Heart Mission

For more than 20 years, the IPA has performed life-saving heart surgery on over 400 patients in Santiago, Dominican Republic.

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Honduras Mission

The IPA is working with Duke to expand their heart surgery mission program in Honduras. We have a mission trip planned for mid-May. Stay tuned for more information.

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Your Mission Trip

The IPA will gladly make donations to qualified charitable organizations who perform cardiac surgery mission work for patients in need.

600+

Patients served

Help Mend a Heart!

Every member of our team is an unpaid volunteer, so please take comfort in knowing that 100% of all donated funds go directly to patient care. Your generosity is so very welcome and will help save lives!

— Latest News —

Machine Learning for In-hospital Mortality Prediction in Critically Ill Patients With Acute Heart Failure

Machine Learning for In-hospital Mortality Prediction in Critically Ill Patients With Acute Heart Failure: A Retrospective Analysis Based on the MIMIC-IV Database

This study developed machine learning (ML) models to predict in-hospital mortality among ICU patients with acute heart failure (AHF) using data from the MIMIC-IV database. Among five tested algorithms, XGBoost showed the highest predictive accuracy (AUC: 0.82) and outperformed traditional clinical scoring systems. The model incorporated 18 clinical variables from the first 24 hours of ICU admission to aid early intervention strategies.

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CytoSorb Filter During Kidney Normothermic

Protocol for a Single-Centre Randomised Pilot Study to Assess the Safety and Feasibility of Adding a CytoSorb Filter During Kidney Normothermic Machine Perfusion to Remove Inflammatory and Immune Mediators Prior to Kidney Transplantation

This pilot study assesses the safety and feasibility of using a CytoSorb filter during kidney normothermic machine perfusion (NMP) before transplantation. The goal is to reduce inflammation-related damage by filtering immune mediators. Twenty patients will be randomized to receive kidneys preserved with or without the filter. Outcomes include immune gene expression, delayed graft function, and kidney performance at intervals post-transplant.

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Comparison of Del Nido and Histidine-Tryptophan-Ketoglutarate

Comparison of Del Nido and Histidine-Tryptophan-Ketoglutarate Cardioplegia Solutions: An Animal Study With Prolonged Ischaemia

This study compares Del Nido (DN) and Bretschneider histidine-tryptophan-ketoglutarate (HTK) cardioplegia solutions in a porcine model of prolonged ischaemia. DN demonstrated superior left ventricular function, spontaneous return to sinus rhythm, and less haemodilution and endothelial dysfunction compared to HTK. Histological and biochemical markers of injury, stress, and apoptosis showed no significant differences, suggesting DN offers enhanced myocardial protection during cardiac surgery.

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