Organ Procurement Organization Perspectives on Normothermic Regional Perfusion Practices: A Qualitative Interview Study

Normothermic regional perfusion (NRP) can increase utilization of organs donated after circulatory death, but implementation varies across U.S. organ procurement organizations (OPOs). Interviews with 20 OPO executives revealed inconsistent hospital acceptance, protocols, data collection, donor-family disclosure, and training. The study concludes that standardized procedures, proactive education, transparency, and cross-organizational collaboration may improve NRP implementation and trust.

September 9, 2026

PerfusionGPT: The Ultimate AI-Powered Resource for Perfusionists

PerfusionGPT 3.0: The Ultimate AI-Powered Resource for Perfusionists

PerfusionGPT is an AI-powered chatbot based on Open-AI’s latest models, specifically designed to provide expert knowledge for perfusionists in cardiac surgery. It serves as a critical resource for both clinical decision-making and educational purposes in the field of perfusion.

September 5, 2026

Quality Indicators for Transcatheter Aortic Valve Implantation in Ontario, Canada: A Population-Based Study

This population-based study evaluated quality indicators for transcatheter aortic valve implantation (TAVI) among 9,748 procedures at 11 Ontario hospitals. Five measurable indicators showed generally high adherence. Heart-team involvement, transfemoral procedures without general anesthesia, and transfemoral access were associated with better outcomes. However, residual confounding suggests patient factors explain much of the observed variation.

September 5, 2026

Propofol-Supplemented Cardioplegic Solution Effect on Myocardial Protection: A Systematic Review and Bayesian Meta-Analysis of Randomized Controlled Trials

This systematic review and Bayesian meta-analysis evaluated whether adding propofol to cardioplegic solution improves myocardial protection during cardiac surgery. Five randomized controlled trials involving 523 patients found no definitive reduction in postoperative troponin or improvement in creatinine, arrhythmias, serious complications, or length of stay. Although Bayesian analysis suggested moderate probabilities of benefit, uncertainty remains too high to support routine use.

September 3, 2026

Designing a Cardiac Arrest System That Includes Extracorporeal Cardiopulmonary Resuscitation: A Contemporary Review

Extracorporeal cardiopulmonary resuscitation (ECPR) can achieve survival approaching 30% for selected patients with refractory out-of-hospital cardiac arrest, but success depends on the entire system of care. This contemporary review examines patient selection, EMS optimization, geographic planning, rapid transport, hospital-based, rendezvous and prehospital ECPR models, specialized cardiac arrest centers, postresuscitation care, cost effectiveness, and continuous quality improvement.

August 31, 2026

Predictive Preoperative Score of Prolonged Mechanical Ventilation After Coronary Artery Bypass Grafting

A study of 2,083 patients undergoing CABG found that 11.6% required prolonged mechanical ventilation for more than 48 hours. Researchers developed a simple preoperative risk score using readily available clinical factors, with risk ranging from 2.9% in the lowest-risk group to 44.3% in the highest. Anemia, severe kidney and ventricular dysfunction, urgent surgery, and other factors predicted increased risk, while risk also rose as cardiopulmonary bypass exceeded about 120 minutes.

August 30, 2026

Blood-Based Versus Crystalloid Cardiopulmonary Bypass Priming in Left Ventricular Assist Device Surgery: Impact on End-Organ Function and Survival

This retrospective study compared blood-based versus crystalloid cardiopulmonary bypass priming in 92 patients undergoing HeartMate 3 LVAD implantation. Blood-based priming was associated with significantly less postoperative right heart failure and delirium and a trend toward less dialysis. Major bleeding was numerically lower, while survival differences were not statistically significant. Prospective randomized trials are needed to confirm these findings.

August 7, 2026

Does Sternal-Sparing Outweigh Prolonged Bypass? Inflammatory Resolution in MICS Versus Median Sternotomy: A SIRI-Based Analysis

A propensity score-matched study of 178 patients undergoing mitral valve surgery compared minimally invasive cardiac surgery (MICS) with conventional median sternotomy. Although MICS required longer operative, cardiopulmonary bypass, and cross-clamp times, patients experienced faster resolution of systemic inflammation by postoperative day 5, measured using the Systemic Inflammation Response Index (SIRI). Early postoperative SIRI also showed promise for predicting pulmonary complications.

August 6, 2026

Impact of Antegrade Selective Cerebral Perfusion Flow Ranges on Clinical and Neurological Outcomes in Aortic Arch Surgery

This retrospective single-center study evaluated 492 adults undergoing aortic arch surgery with bilateral selective antegrade cerebral perfusion (SACP). Patients were grouped by indexed cerebral perfusion flow (<10, 10–15, or >15 mL/kg/min). No significant differences were found in 30-day mortality, permanent neurological dysfunction, or transient neurological deficits across flow ranges. The findings support individualized intraoperative perfusion management while maintaining recommended flow targets.

August 6, 2026

Comparable Survival Over an Extended Follow-Up After On-Pump Versus Off-Pump Coronary Artery Bypass Grafting: A Propensity Score-Matched Cohort

Researchers evaluated long-term outcomes after on-pump (ONCAB) and off-pump (OPCAB) coronary artery bypass grafting in 2,935 patients treated between 1999 and 2016. After propensity score matching, 402 OPCAB patients were compared with 804 ONCAB patients over follow-up extending nearly 24 years. Survival and cardiovascular mortality were similar between groups, suggesting that when performed by experienced surgeons and appropriately selected patients, both techniques provide comparable long-term outcomes.

June 16, 2026

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