Incidence, Risk Factors and Outcomes of Postoperative Acute Kidney Injury Requiring Dialysis After Cardiac Surgery: A Retrospective Study from the National Heart Institute of Malaysia

This retrospective Malaysian cohort study examined 6,779 adult cardiac surgery patients and found that 4.5% developed postoperative acute kidney injury requiring dialysis. Risk was higher in patients with chronic kidney disease, urgent surgery, diabetes, reoperation, and longer ICU stay. Dialysis-requiring AKI was linked to sharply increased mortality, especially among patients without baseline CKD, highlighting the need for earlier renal risk stratification and kidney-protective perioperative care.

April 6, 2026

The Combined Use of HA380 Hemoperfusion in Cardiopulmonary Bypass Alleviates Postoperative Inflammatory Response and Organ Dysfunction Following Cardiac Surgery

This randomized single-center trial evaluated 65 patients undergoing elective cardiac surgery with cardiopulmonary bypass and found that adding the HA380 hemoperfusion cartridge reduced early postoperative inflammatory cytokines, including IL-1β, IL-6, IL-8, and IL-10. The HA380 group also had lower vasoactive-inotropic requirements and better short-term liver and kidney laboratory markers, although ICU ventilation time and ICU stay were not significantly improved.

April 6, 2026

Standardization of In-Vitro Evaluation of Extracorporeal Life Support (ECLS) Devices for Research and Development

This guideline article argues that extracorporeal life support device testing should follow standardized in-vitro protocols so results can be reproduced, compared across research groups, and translated more effectively into practice. It outlines reporting criteria, relevant ISO standards, preferred test conditions, and key considerations for pumps, oxygenators, cannulae, tubing, hemolysis, and thrombogenicity assessment.

April 5, 2026

Quality Management of Comprehensive Blood Conservation Strategies During Cardiopulmonary Bypass in Pediatric Cardiac Surgery

This retrospective single-center study evaluated 9,792 children aged 14 years or younger undergoing cardiac surgery with cardiopulmonary bypass. After implementation of a quality-managed, multimodal blood conservation program, matched analysis showed lower PRBC and plasma transfusion rates, smaller CPB priming volumes, and fewer postoperative complications, especially liver injury and acute kidney injury, without increased mortality or longer recovery.

April 2, 2026

Bright Operating Room Scene for Normoxic vs Hyperoxic CABG Reperfusion

Normoxic versus Hyperoxic Reperfusion: A Retrospective Study of Ischemia–Reperfusion Injury in Patients Undergoing On-Pump Coronary Artery Bypass Grafting

This retrospective study compared normoxic and hyperoxic reperfusion strategies in 50 patients undergoing elective on-pump CABG. Although oxygen delivery was similar between groups, normoxic management was associated with lower postoperative myocardial injury, better cardiac index, smaller declines in ejection fraction, and lower oxidative stress. The findings suggest that physiology-guided oxygenation may reduce ischemia–reperfusion injury during cardiopulmonary bypass.

April 1, 2026

The Impact of Re-operation on Aortic Arch Reconstructive Surgery: Evidence from a Multicentre, National Registry

This multicenter Canadian registry study examined 2,481 patients who underwent aortic arch reconstruction between 2002 and 2021, including 374 redo cases after prior open-heart surgery. Despite a higher comorbidity burden, redo surgery was not associated with significantly higher overall operative mortality or major morbidity than primary surgery. Risk increased with older age, acute dissection or rupture, and longer cardiopulmonary bypass time.

April 1, 2026

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