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IPA

Philanthropy, Passion & Education International Perfusion Association The International Perfusion Association (IPA), a 501(c)(3) non-profit organization, is dedicated to enhancing education and supporting global cardiac surgery initiatives. Our mission is to amplify our philanthropic efforts by organizing cardiac surgery missions, assisting those engaged in similar endeavors, and bolstering local educational programs. We welcome individuals who are eager to make a meaningful difference in the world to join us in our cause. Make a Donation
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Heart to Heart Mission

For more than 20 years, the IPA has performed life-saving heart surgery on over 400 patients in Santiago, Dominican Republic.

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Ecuador Mission

The IPA is working with Harvard / MGH to expand their heart surgery mission program in Ecuador. We have a mission trip planned for October 2026. Stay tuned for more information.

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Your Mission Trip

The IPA will gladly make donations to qualified charitable organizations who perform cardiac surgery mission work for patients in need.

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700+ Patients

Help Mend a Heart!

Every member of our team is an unpaid volunteer, so please take comfort in knowing that 100% of all donated funds go directly to patient care. Your generosity is so very welcome and will help save lives!
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— Latest News —

AI-Driven Cardiac Surgery Future

Artificial Intelligence in Adult Cardiovascular Medicine and Surgery: Real-World Deployments and Outcomes

Artificial intelligence (AI) is transforming adult cardiovascular medicine and surgery by enhancing diagnostics, surgical planning, intraoperative precision, and postoperative monitoring. Tools such as AI-ECG, automated imaging, and predictive analytics improve risk stratification and outcomes. While real-world deployments show promise, challenges including data quality, bias, and limited prospective validation remain barriers to widespread adoption.

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April 1, 2026
ECMO Anticoagulation Innovation in Critical Care

Alternate and Emerging Anticoagulation Strategies for Extracorporeal Membrane Oxygenation: A Scoping Review

This scoping review maps the evidence on ECMO anticoagulation strategies beyond unfractionated heparin. Across 135 included records, direct thrombin inhibitors—especially bivalirudin—were the most studied alternatives, while nafamostat, prostaglandin E1, circuit modifications, anticoagulation-free protocols, and newer monitoring tools remain emerging areas. The authors conclude that ECMO anticoagulation is shifting toward more personalized, diversified management.

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March 31, 2026
Bridging the Distance: Pediatric ECMO Access Across America

State and Regional Variation in Access to Pediatric Extracorporeal Membrane Oxygenation

This geospatial cross-sectional study examined how access to pediatric extracorporeal membrane oxygenation varies across U.S. states and Pediatric Emergency Referral Regions. Researchers identified 258 pediatric ECMO centers and 169 ECPR centers, finding major differences in direct access, especially in rural areas. Although interfacility transport made ECMO access nearly universal in many places, access to ECPR remained very limited for most children.

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March 30, 2026
Sevoflurane Delivery During Cardiopulmonary Bypass

Estimated End-Tidal Sevoflurane Concentration to Maintain Optimal Anesthetic Depth During Cardiopulmonary Bypass: A Meta-Analysis

This meta-analysis examined how much end-tidal sevoflurane is needed to maintain appropriate anesthetic depth during cardiopulmonary bypass. Across five prospective studies involving 129 adults, the pooled estimate was 0.88 vol% for a BIS target of 40–60. Older patients required less sevoflurane, while body temperature did not significantly change dosing needs. The findings offer a practical reference point, although evidence certainty remained limited by heterogeneity and small study sizes.

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March 29, 2026
Mechanical Circulatory Support in Cardiogenic Shock

Mechanical Circulatory Support in Cardiogenic Shock: A Contemporary Head-to-Head Comparison

This mini review compares the three main temporary mechanical circulatory support options for cardiogenic shock: Impella, venoarterial extracorporeal life support (VA-ECLS), and intra-aortic balloon pump (IABP). It explains each device’s physiology, indications, risks, and evidence base, then proposes practical algorithms for selection, escalation, de-escalation, and anticoagulation to help clinicians tailor support to shock severity and cause.

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March 28, 2026
Safer Bypass: Oxygenator Design and Delirium Risk in CABG

Oxygenator-Related Gaseous Microemboli and Postoperative Delirium After On-Pump Coronary Artery Bypass Grafting: A Prospective Cohort Study

This prospective cohort study examined 102 adults undergoing first-time isolated on-pump CABG and compared three membrane oxygenators: Capiox FX25, Inspire 8, and Inspire 8F. The Capiox FX25 showed the lowest arterial gaseous microemboli volume and the best volume reduction, while postoperative delirium occurred in 29.4% overall and was least frequent with Capiox FX25. The findings suggest oxygenator choice may influence neurocognitive outcomes after cardiac surgery.

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March 28, 2026
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