Philanthropy, Passion & Education International Perfusion Association The International Perfusion Association (IPA), a 501(c)(3) non-profit organization, is dedicated to enhancing education and supporting global cardiac surgery initiatives. Our mission is to amplify our philanthropic efforts by organizing cardiac surgery missions, assisting those engaged in similar endeavors, and bolstering local educational programs. We welcome individuals who are eager to make a meaningful difference in the world to join us in our cause. Make a Donation
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Heart to Heart Mission

For more than 20 years, the IPA has performed life-saving heart surgery on over 400 patients in Santiago, Dominican Republic.

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Ecuador Mission

The IPA is working with Harvard / MGH to expand their heart surgery mission program in Ecuador. We have a mission trip planned for October 2026. Stay tuned for more information.

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Your Mission Trip

The IPA will gladly make donations to qualified charitable organizations who perform cardiac surgery mission work for patients in need.

700+ Patients

Help Mend a Heart!

Every member of our team is an unpaid volunteer, so please take comfort in knowing that 100% of all donated funds go directly to patient care. Your generosity is so very welcome and will help save lives!

— Latest News —

MIDCAB vs Drug-Eluting Stent: Two Paths to LAD Revascularization

Revascularization of Left Anterior Descending Artery with Minimally Invasive Direct Coronary Artery Bypass Graft vs. Drug Eluting Stents: A Retrospective, Two-Center Study

This retrospective two-center study compared long-term outcomes of minimally invasive direct coronary artery bypass (MIDCAB) with drug-eluting stent (DES) percutaneous coronary intervention for left anterior descending (LAD) artery disease. Among matched patient groups, MIDCAB resulted in significantly lower rates of recurrent angina and repeat revascularization within two years. However, long-term survival up to 20 years was similar between both treatments. The findings support MIDCAB as a durable alternative for LAD revascularization.

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Global Research Trends and Hotspots in Extracorporeal Membrane Oxygenation

Global Research Trends and Hotspots in Extracorporeal Membrane Oxygenation for Cardiogenic Shock: A Bibliometric Review and Knowledge Mapping Approach (1990–2024)

This bibliometric study analyzed global research trends in extracorporeal membrane oxygenation (ECMO) for cardiogenic shock from 1990–2024. Using 701 publications from 55 countries, the authors mapped collaborations, influential institutions, and evolving research themes. Major topics include postcardiotomy shock, extracorporeal cardiopulmonary resuscitation (ECPR), acute myocardial infarction–related shock, and ECMO bridging to transplant. Research focus has shifted toward predictive scoring systems, standardized protocols, and long-term patient outcomes.

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Viscoelastic Monitoring Guiding Hemostasis During Cardiac Surgery

A Prospective Analysis of Viscoelastic Assays, Platelet Aggregometry, and Standard Laboratory Tests in Predicting Perioperative Blood Loss in Cardiac Surgery

This prospective observational study of 79 cardiac surgery patients evaluated whether viscoelastic testing (ROTEM), platelet aggregometry, or standard coagulation tests best predict perioperative bleeding. Clot firmness measured by FIBTEM A10 strongly correlated with blood loss using the Hb/kg Index, while platelet count, platelet aggregation, and conventional tests did not. A FIBTEM A10 cutoff of 12 mm accurately detected hypofibrinogenemia, supporting fibrinogen-focused transfusion strategies.

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Kidneys at Risk During Cardiac Bypass Surgery

Risk Factors for Acute Kidney Injury After Coronary Artery Bypass Graft Surgery: A Systematic Review and Meta-Analysis

Acute kidney injury (AKI) is a serious complication after coronary artery bypass graft (CABG) surgery. This systematic review and meta-analysis analyzed 17 observational studies including 33,809 patients to identify key predictors of AKI. Significant risk factors included advanced age, prolonged cardiopulmonary bypass duration, diabetes, intra-aortic balloon pump use, and red blood cell transfusion. Recognizing these risks may help clinicians improve perioperative management and reduce kidney complications after cardiac surgery.

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Prevalence of Musculoskeletal Disorders Among Perfusion Staff

Prevalence of Musculoskeletal Disorders Among Perfusion Staff in Germany

This nationwide cross-sectional study investigated the prevalence of musculoskeletal disorders (MSDs) among perfusionists working in German cardiac centers. Using the Nordic Musculoskeletal Questionnaire, researchers surveyed 287 professionals. Results showed that 86% reported MSD symptoms within the past year, most commonly in the lower back and neck. Increasing age and years of professional experience were associated with higher prevalence, highlighting the need for ergonomic improvements and occupational health strategies.

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Heparin Anticoagulation Management During Cardiopulmonary Bypass

Contemporary Clinical Practices in Anticoagulation Management During Cardiopulmonary Bypass: A Europe-Wide Survey

A Europe-wide survey of 114 cardiac surgery centers across 29 countries evaluated current anticoagulation practices during cardiopulmonary bypass. Most centers reported standardized heparin protocols and commonly used a 300 IU/kg initial dose with ACT targets of 400–480 seconds. However, substantial variability existed in protamine reversal strategies, post-reversal ACT targets, and transfusion decision-making, highlighting gaps between guidelines and real-world practice. These findings identify key opportunities for standardizing perioperative anticoagulation management in cardiac surgery. 

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