Urinary Collectrin as Promising Biomarker for Acute Kidney Injury in Patients Undergoing Cardiac Surgery

December 26, 2023 No Comments

This study explores urinary collectrin as a potential biomarker for early detection of acute kidney injury (AKI) in patients undergoing cardiac surgery with cardiopulmonary bypass. It found significant perioperative changes in collectrin levels, particularly on postoperative day 1, indicating its promise for timely AKI diagnosis and intervention, though further research is needed for clinical validation.

Mechanical Circulatory Support in Cardiogenic Shock

December 26, 2023 No Comments

The abstract outlines the evolving management of cardiogenic shock, highlighting the transition to using temporary mechanical circulatory support (t-MCS) like IABP, VA-ECMO, Impella, and ECPELLA, informed by advances in circulatory physiology. It emphasizes the importance of selecting appropriate t-MCS devices based on patient-specific conditions, shock stage, and risk, guided by hemodynamic monitoring and a multidisciplinary team approach.

Association Between Cardiopulmonary Bypass Time and Mortality Among Patients With Acute Respiratory Distress Syndrome After Cardiac Surgery

December 24, 2023 No Comments

Longer cardiopulmonary bypass (CPB) times were associated with increased ICU and in-hospital mortality, as well as longer ICU stays, in patients who developed acute respiratory distress syndrome (ARDS) after cardiac surgery. This study suggests that CPB duration is a significant predictor of short-term mortality in these patients, with times over 160.5 minutes increasing the risk of worse outcomes.

Development of New Colloid Osmotic Pressure Measurement Method Using Ultrafiltration Membrane During Cardiopulmonary Bypass

December 22, 2023 No Comments

A study developed an ultrafiltration membrane method to measure colloid osmotic pressure (COP) and compared it with colloidal osmometer measurements, finding high accuracy, reproducibility, and positive correlation with existing methods. This new method shows potential for improved COP monitoring in clinical settings, suggesting implications for future research and clinical applications.

Impact of Pre-Bypass Ultrafiltration on Prime Values and Clinical Outcomes in Neonatal and Infant Cardiopulmonary Bypass

December 21, 2023 No Comments

Pre-bypass Ultrafiltration (PBUF) was found to standardize and make more physiologic the values for electrolytes, glucose, and lactate in blood primes used for cardiopulmonary bypass in congenital cardiac surgery, without significantly affecting in-hospital outcomes. This retrospective study compared patients ≤ 1 year old undergoing cardiac surgery with PBUF to those without, showing significant improvements in the physiologic values of PBUF-treated circuits.

Our Initial Experience of Monitoring the Autoregulation of Cerebral Blood Flow During Cardiopulmonary Bypass

December 20, 2023 No Comments

This study investigates the application of the cerebral oxygenation index (COx) in monitoring cerebral blood flow (CBF) autoregulation during cardiopulmonary bypass surgeries. Despite the complexity and challenges involved, the study emphasizes the critical analysis of COx, highlighting limitations and suggesting caution before its implementation in clinical practice.

Pro: Individualized Optimal Perfusion Pressure- Maximizing Patient Care During Cardiopulmonary Bypass

December 20, 2023 No Comments

Exploring techniques like multimodal intravenous anesthesia guided by electroencephalogram can enhance perfusion maintenance within the auto-regulatory range. By adopting an individualized approach to perfusion targets on CPB, we can improve outcomes and enhance patient care.

Cerebral Microhemorrhages in Children with Congenital Heart Disease: Prevalence, Risk Factors, and Impact on Neurodevelopmental Outcomes

December 19, 2023 No Comments

Cerebral microhemorrhages (CMH) are frequently seen after neonatal bypass heart surgery, but it remains unknown if CMH are a benign finding or constitute injury. Herein, we investigate the risk factors for developing CMH and their clinical significance.

Comparison of 6% Hydroxyethyl Starch 130/0.4 and Ringer’s Lactate as Priming Solutions in Patients Undergoing Isolated Open Heart Valve Surgery: A Double-Blind Randomized Controlled Trial

December 18, 2023 No Comments

This study compared the outcomes of heart valve surgery patients undergoing cardiopulmonary bypass with two different priming solutions: 6% hydroxyethyl starch (HES) 130/0.4 and ringer’s lactate (RL). The results indicate that using HES in addition to RL for priming increased the risk of blood product transfusion during hospitalization compared to using RL alone in this patient population.

Cardiopulmonary Bypass Management and Acute Kidney Injury in Cardiac Surgery Patients

December 15, 2023 No Comments

Cardiopulmonary bypass (CPB) ensures tissue oxygenation during cardiac surgery. New technology allows continuous registration of CPB variables during the operation. The aim of the present investigation was to study the association between CPB management and the risk of postoperative acute kidney injury (AKI).