Explore articles, research, and perspectives from the International Perfusion Association.
A review of bloodless medicine connects anemia treatment, perfusion blood conservation, and individualized consent, with an update to current religious guidance.
A 60-patient randomized trial found less drainage and fewer red-cell transfusions with topical TXA mist after on-pump CABG, with important safety and reporting limits.
A systematic review and expert opinion paper proposes a TEG 6s framework for bleeding adult cardiac surgical patients, highlighting assay differences and the need
A retrospective comparison links femoral cannulation before redo sternotomy with lower red-cell use and fewer reported cardiovascular complications. Important inconsistencies in patient counts, follow-up,
A case report of temperature-dependent red-cell clumping during valve surgery highlights cold-agglutinin recognition, changes to bypass and cardioplegia, and the limits of single-patient evidence.
The ECSTATIC feasibility trial compared platelet transfusion triggers of 50 and 90 × 10⁹/L in 50 children on ECMO, supporting a larger definitive trial.
A 166-patient study links preoperative platelet-to-lymphocyte ratio with prolonged inotropic support after minimally invasive cardiac surgery. Predictive performance was modest.
A randomized study compared Angel and Magellan PRP preparation in 60 cardiac surgery cases. Both met the sixfold target on average, with individual variability.
Seattle Children’s describes modified blood priming in 26 patients weighing 2.0–6.5 kg. Calculated red-cell priming combined with autologous priming reduced crystalloid exposure; mean PRBC
A secondary ECSTATIC analysis examined 161 platelet transfusions in 27 children on ECMO. The median platelet increment was 19 × 10⁹/L. Pathogen-reduced products were
This guideline article argues that extracorporeal life support device testing should follow standardized in-vitro protocols so results can be reproduced, compared across research groups,
This retrospective single-center study evaluated 9,792 children aged 14 years or younger undergoing cardiac surgery with cardiopulmonary bypass. After implementation of a quality-managed, multimodal
