The Northern New England Rapid Deployment Valve Experience: Survival and Procedural Outcomes From 2015 to 2021

February 7, 2024 No Comments

This study examines the outcomes of rapid deployment aortic valve replacement (rdAVR) compared to stented aortic valve replacement (sAVR) in patients undergoing isolated aortic valve replacement or combined procedures with coronary artery bypass grafting from 2015 to 2021. Utilizing data from the Northern New England Cardiovascular Database, the research found that rdAVR offers significant advantages in terms of shorter cross-clamp and cardiopulmonary bypass times without compromising immediate postoperative gradients or long-term survival. However, rdAVR is associated with higher pacemaker rates, especially in larger valve sizes. The study concludes that rdAVR is a viable and safe alternative to sAVR, necessitating further long-term follow-up.

Midterm Clinical Outcomes of Reimplantation Versus Remodeling Valve-Sparing Aortic Root Replacement in Patients With Connective Tissue Disorders: A Meta-Analysis

February 3, 2024 No Comments

This meta-analysis compared the midterm clinical outcomes of reimplantation versus remodeling techniques for valve-sparing aortic root replacement in patients with connective tissue disorders, finding no significant difference in mortality, reoperation rates, or postoperative aortic regurgitation. However, a sensitivity analysis excluding annuloplasty suggested that reimplantation may be superior to remodeling alone, indicating that further research is needed to fully evaluate these surgical techniques in this patient demographic.

Meta-Analysis of the Performance of AI-Driven ECG Interpretation in the Diagnosis of Valvular Heart Diseases

February 2, 2024 No Comments

Artificial intelligence (AI) applied to electrocardiogram (ECG) interpretation shows high accuracy for early detection of valvular heart diseases (VHDs), based on a meta-analysis of data from 713,537 patients, with pooled accuracy and sensitivity of 81% and 83%, respectively. However, the low positive predictive value (PPV) of 13% suggests that AI should be used in conjunction with clinical judgment for VHD screening in primary care settings.

Transcatheter Aortic Valve Implantation to Treat Degenerated Aortic, Mitral and Tricuspid Bioprosthesis

January 31, 2024 No Comments

Transcatheter aortic valve implantation (TAVI) is now a widely accepted treatment for a broad range of patients with aortic valve stenosis, including those at low surgical risk and with previously contraindicated conditions like bicuspid valves. It has also evolved to treat degenerated bioprosthetic valves in the aortic, mitral, and tricuspid positions, offering an alternative to redo surgery.

Clinical Outcomes Following Transcatheter Mitral Valve-in-Valve Replacement Using a Meril Myval Transcatheter Heart Valve

January 28, 2024 No Comments

This study reports on the outcomes of twenty patients who underwent transcatheter mitral valve-in-valve (TMViV) replacement using the Meril Myval transcatheter valve at a tertiary care centre in India, focusing on in-hospital, 30-day, and 1-year results. The findings show a 100% technical success rate, no significant leaks or obstructions, a 10% all-cause mortality at 1 year, and improved NYHA class in survivors, indicating that the procedure is safe and effective with low short-term and medium-term mortality.

Relationship Between Difference of Preoperative and Cardiopulmonary Bypass Mean Arterial Pressure, and Acute Kidney Injury in Cardiac Surgical Patients Undergoing Valve Surgery

January 8, 2024 No Comments

In a study of 112 high-risk cardiac surgery patients, it was found that the difference in pre-operative and on-bypass mean arterial pressure (MAP) and cardiopulmonary bypass (CPB) flows did not significantly predict early post-surgical acute kidney injury (CSA-AKI). However, baseline serum levels of Neutrophil gelatinase-associated lipocalin (NGAL) and its early post-surgical percent change were strong independent predictors of CSA-AKI development, suggesting its potential as a useful biomarker in identifying patients at risk.

Myocardial Protection with Phosphocreatine in High-Risk Cardiac Surgery Patients: A Randomized Trial

January 5, 2024 No Comments

This study tested if phosphocreatine (PCr) reduces troponin I levels in cardiac surgery patients with prolonged aortic clamping and cardiopulmonary bypass. Although PCr was safely administered, it did not lead to a decrease in troponin I concentration or improve other clinical outcomes after surgery.

New Approach for Combined Aortic Valve and Coronary Procedures Through the Left Anterior Minithoracotomy

January 5, 2024 No Comments

A novel technique for aortic valve replacement and coronary artery bypass grafting through left anterior minithoracotomy has been successfully used in six patients, demonstrating technical feasibility and effectiveness without major complications. This approach, which allows simultaneous valve and multivessel coronary procedures, requires further study in a larger patient population to understand its potential limitations fully.

Outcomes of Barlow Mitral Valve Repaired by Robot-Assisted Keyhole Surgery

January 4, 2024 No Comments

This study analyzed the outcomes of robot-assisted keyhole surgery for Barlow mitral valve repair in 124 patients, highlighting the use of the loop technique for neochordae implantation and minimal resections. The results demonstrated a high success rate with low complication and reoperation rates, suggesting that this robotic technique is effective and safe for treating Barlow mitral valve.

Percutaneous Debulking of Tricuspid Valve Infective Endocarditis Vegetations Using a Large Bore Manual Aspiration Device – AlphaVac

December 31, 2023 No Comments

While most infectious endocarditis cases are managed medically, non-responsive patients or those with complications like septic emboli may need mechanical interventions such as AngioVac, which has limitations like the need for a perfusionist and large-bore accesses. The AlphaVac system, omitting the motor element, offers a simpler alternative for manual percutaneous aspiration of tricuspid valve vegetations, as demonstrated in two reported cases.

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The Northern New England Rapid Deployment Valve Experience: Survival and Procedural Outcomes From 2015 to 2021

Midterm Clinical Outcomes of Reimplantation Versus Remodeling Valve-Sparing Aortic Root Replacement in Patients With Connective Tissue Disorders: A Meta-Analysis

Meta-Analysis of the Performance of AI-Driven ECG Interpretation in the Diagnosis of Valvular Heart Diseases

Transcatheter Aortic Valve Implantation to Treat Degenerated Aortic, Mitral and Tricuspid Bioprosthesis

Clinical Outcomes Following Transcatheter Mitral Valve-in-Valve Replacement Using a Meril Myval Transcatheter Heart Valve

Relationship Between Difference of Preoperative and Cardiopulmonary Bypass Mean Arterial Pressure, and Acute Kidney Injury in Cardiac Surgical Patients Undergoing Valve Surgery

Myocardial Protection with Phosphocreatine in High-Risk Cardiac Surgery Patients: A Randomized Trial

New Approach for Combined Aortic Valve and Coronary Procedures Through the Left Anterior Minithoracotomy

Outcomes of Barlow Mitral Valve Repaired by Robot-Assisted Keyhole Surgery

Percutaneous Debulking of Tricuspid Valve Infective Endocarditis Vegetations Using a Large Bore Manual Aspiration Device – AlphaVac

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