Explore articles, research, and perspectives from the International Perfusion Association.
This systematic review and Bayesian meta-analysis evaluated whether adding propofol to cardioplegic solution improves myocardial protection during cardiac surgery. Five randomized controlled trials involving
This retrospective study compared normoxic and hyperoxic reperfusion strategies in 50 patients undergoing elective on-pump CABG. Although oxygen delivery was similar between groups, normoxic
This experimental rat-heart study tested whether ranolazine protects the myocardium through pathways similar to ischemic preconditioning. Using a Langendorff ischemia-reperfusion model, ranolazine reduced infarct
This bibliometric analysis reviews 372 studies on normothermic regional perfusion (NRP) from 2014–2025, showing rapid growth in research and global adoption. The United States
Normothermic regional perfusion (NRP) is reshaping controlled donation after circulatory death (cDCD) liver transplantation. By restoring oxygenated blood flow after death declaration, NRP reduces
This comprehensive review explores how cardioplegia actively protects the myocardium during coronary artery bypass grafting. Beyond inducing cardiac arrest, cardioplegic solutions modulate calcium homeostasis,
This review explores the use of Del Nido cardioplegia in adult cardiac surgery, originally developed for pediatric use. It outlines its composition, benefits over
This study compares two cardioplegic solutions—HTK and Del Nido—for their impact on cerebral inflammation in a porcine cardiopulmonary bypass model. Results showed that while
This study examines outcomes of donation after circulatory death (DCD) heart transplantation using thoracoabdominal normothermic regional perfusion (TA-NRP). A retrospective analysis of 32 recipients
This study explores the potential benefits of gradual reperfusion in cardiac surgery patients experiencing cardioplegia-induced cardiac arrest, aiming to reduce ischemia-reperfusion injury. Fifty elective
This systematic review and meta-analysis evaluates the effectiveness of remote ischemic preconditioning (RIPC) in preventing cognitive dysfunction after coronary artery bypass grafting (CABG) with
This case report examines the efficacy of adjunctive hemoadsorption using CytoSorb® in managing ischemia-reperfusion injury (IRI) following a near-drowning incident. Highlighting a critical case
