Explore articles, research, and perspectives from the International Perfusion Association.
Six randomized trials found no significant improvement in acute kidney injury or other clinical outcomes with intraoperative hemoadsorption. Trial sequential analysis shows that the
A retrospective cohort of 200 adults describes normothermic cardiopulmonary bypass guided by indexed flow, cerebral oximetry, and oxygen delivery, with vasopressors reserved for clinical
A prospective study of 60 adults compared PerfSCORE with NIRS and S100B after open-heart surgery. PerfSCORE was associated with early mortality, but only six
A prospective study of 100 adults found that cardiopulmonary bypass lasting more than 120 minutes was associated with higher early postoperative acute kidney injury
This systematic review and Bayesian meta-analysis evaluated whether adding propofol to cardioplegic solution improves myocardial protection during cardiac surgery. Five randomized controlled trials involving
A study of 2,083 patients undergoing CABG found that 11.6% required prolonged mechanical ventilation for more than 48 hours. Researchers developed a simple preoperative
This retrospective study compared blood-based versus crystalloid cardiopulmonary bypass priming in 92 patients undergoing HeartMate 3 LVAD implantation. Blood-based priming was associated with significantly
Researchers evaluated long-term outcomes after on-pump (ONCAB) and off-pump (OPCAB) coronary artery bypass grafting in 2,935 patients treated between 1999 and 2016. After propensity
This randomized trial compared topical intrapericardial tranexamic acid (TXA) with standard intravenous TXA in 492 adults undergoing cardiac surgery with cardiopulmonary bypass. Topical TXA
This systematic review and meta-analysis evaluated whether hyperoncotic 20%–25% human albumin affects acute kidney injury after adult on-pump cardiac surgery. Across four studies including
This systematic review examines anticoagulation monitoring during cardiopulmonary bypass in patients with antiphospholipid syndrome, a high-risk prothrombotic condition that can make activated clotting time
This single-center retrospective study of 381 adult heart transplants found that prolonged oxygen extraction ratio, or O2ER, above 0.20 during cardiopulmonary bypass was linked
