Explore articles, research, and perspectives from the International Perfusion Association.
A prospective study of 94 CABG patients linked coronary sinus lactate above 3 mmol/L five minutes after reperfusion with more treated postoperative atrial fibrillation.
A Colombian study of 179 adults undergoing isolated aortic valve replacement found lower modeled costs with Del Nido than Custodiol cardioplegia. Thirty-day survival was
A 103-patient retrospective Bentall study associated hybrid cardioplegia with less drainage and fewer bleeding re-explorations, without significant transfusion or mortality differences.
A randomized trial of 58 adults compared lactated Ringer’s–based modified del Nido with Custodiol cardioplegia. Modified del Nido produced lower 24-hour troponin I, faster
In a randomized trial of 60 adults undergoing CABG for left main coronary artery disease, combined antegrade–retrograde blood cardioplegia did not significantly reduce peak
This systematic review and Bayesian meta-analysis evaluated whether adding propofol to cardioplegic solution improves myocardial protection during cardiac surgery. Five randomized controlled trials involving
This experimental rat-heart study tested whether ranolazine protects the myocardium through pathways similar to ischemic preconditioning. Using a Langendorff ischemia-reperfusion model, ranolazine reduced infarct
This retrospective single-center study compared four cardioplegia strategies in 543 patients undergoing minimally invasive aortic valve replacement from 2010 to 2025. After inverse probability
This propensity score-matched, single-center study compared Custodiol and Del Nido cardioplegia in 778 patients undergoing minimally invasive mitral valve repair. Del Nido was linked
This 20-year single-center study of 528 heart transplant recipients compared three preservation solutions: Celsior, HTK-Custodiol, and St Thomas. HTK-Custodiol was associated with a significantly
This retrospective cohort study from a Malaysian tertiary cardiac center compares Custodial-HTK cardioplegia with conventional blood cardioplegia in elective on-pump cardiac surgery. Although Custodial-HTK
This comprehensive review examines alternative crystalloid and whole-blood base solutions for del Nido cardioplegia, including normal saline, lactated Ringer’s, plain Ringer’s, Isolyte S, Ionosteril,
