Neutrophil Percentage to Albumin Ratio Is Associated With In-Hospital Mortality in Patients With Acute Type A Aortic Dissection

This study found that a higher neutrophil percentage to albumin ratio (NPAR) on hospital admission significantly predicts in-hospital mortality in patients undergoing surgery for acute type A aortic dissection (AAAD). Among 813 patients, higher NPAR levels correlated with increased risk of death, acute kidney injury, and longer ICU stays. NPAR outperformed neutrophils or albumin alone in prognostic value, suggesting it as a valuable, accessible clinical biomarker.

June 5, 2025

Evaluation of Intraoperative and Postoperative Blood Cell Salvage Use in Cardiac Surgery with Cardiopulmonary Bypass

This study investigates the impact of using blood cell salvage (BCS) during and after cardiac surgery with cardiopulmonary bypass (CPB). Among 41 patients, those using BCS showed significantly improved hemoglobin and hematocrit levels, fewer red blood cell transfusions, lower infection rates, and shorter hospital stays. The findings support integrating BCS into Patient Blood Management strategies for better clinical outcomes.

June 3, 2025

Comparative Efficacy of Blood Salvage Techniques After Cardiopulmonary Bypass: Centrifugation, Modified Ultrafiltration, and Hemobag Systems in Adult Cardiac Surgery

Four studies explore blood conservation strategies following cardiopulmonary bypass (CPB) in adult cardiac surgery. Techniques like centrifugation (CF), modified ultrafiltration (MUF), and Hemobag (HB) processing vary in their effectiveness. MUF and HB methods consistently reduce postoperative transfusions and improve hematologic markers compared to CF, supporting their broader use in adult cardiac surgical care.

May 20, 2025

Outcomes of a Standardized Protocol on the Management of Acute Type A Aortic Dissection: A Retrospective Cohort Study

This retrospective study assessed a standardized surgical protocol implemented in 2016 for managing acute Type A aortic dissection (AAAD). Comparing pre- and post-protocol cohorts, the study found that standardized techniques improved consistency in surgical approach, reduced rates of aortic reoperations and dilations, and introduced safer cannulation and perfusion strategies. Mortality rates remained statistically unchanged, but the protocol significantly enhanced surgical outcomes.

May 15, 2025

Clinical and Preclinical Evidence on a Novel Percutaneous Pulsatile Ventricular Assist Device (PulseCath): Protocol for a Scoping Review

This protocol outlines a scoping review to explore the clinical and preclinical applications of PulseCath, a novel percutaneous pulsatile ventricular assist device. Designed to bridge the gap between intra-aortic balloon pumps and Impella systems, PulseCath offers intermediate support for patients with hemodynamic instability. The review will systematically evaluate its hemodynamic effects, pathophysiological basis, and safety profile.

May 13, 2025

Del Nido Cardioplegia in Adult Cardiac Surgery: A Narrative Review

This review explores the use of Del Nido cardioplegia in adult cardiac surgery, originally developed for pediatric use. It outlines its composition, benefits over traditional blood cardioplegia, and its mechanism in protecting the myocardium from ischemia-reperfusion injury. The article compiles data showing its efficacy in reducing cross-clamp times, myocardial injury, and transfusion requirements, with comparable or improved clinical outcomes.

May 13, 2025

Revolutionizing Cardiovascular Interventions With Artificial Intelligence

This editorial outlines how artificial intelligence (AI) is transforming cardiovascular interventions by enhancing procedural planning, democratizing medical expertise, and expediting device development. AI-driven tools improve diagnostic accuracy, support training via simulation, and enable the creation of digital twins for personalized treatment planning. The article emphasizes AI’s potential to foster global equity in healthcare access and improve patient outcomes.

May 5, 2025

Predictors of Prolonged Intensive Care Unit Stay and In-Hospital Mortality Following Cardiac Surgery: An Integrated Analysis from the PROCARD-ATI Study

This study analyzed 130 adult cardiac surgery patients to identify perioperative predictors of prolonged ICU stays and in-hospital mortality. Results revealed aortic cross-clamp time (AXCT) as the sole independent predictor of ICU stays ≥7 days, with a threshold of 110 minutes. For mortality, prolonged cardiopulmonary bypass time (CPBT), emergency surgery, and higher AXCT were key predictors. The findings suggest practical intraoperative benchmarks to enhance surgical strategies and outcomes.

April 27, 2025

Impact of Prolonged Cardiopulmonary Bypass on Gastrointestinal Complications in Cardiac Surgery: A Retrospective Cohort Study

This retrospective cohort study assessed the effect of prolonged cardiopulmonary bypass (CPB ≥ 120 minutes) on gastrointestinal complications (GICs) after cardiac surgery. Analyzing 1,444 patients and using propensity score matching, the study found a significantly higher rate of GICs in the prolonged CPB group. Key risk factors included hypertension, lower left ventricular ejection fraction (LVEF), and undergoing aortic surgery.

April 17, 2025

The Past, Present, and Future of Off-Pump Coronary Artery Bypass Grafting

This review traces the evolution and prospects of off-pump coronary artery bypass grafting (OPCAB). Despite early skepticism due to technical difficulty, OPCAB offers major advantages for high-risk patients, including reduced stroke risk and faster recovery. Modern trials and meta-analyses show comparable or superior outcomes to on-pump CABG when performed by experienced surgeons. Emphasis is placed on arterial grafting, no-touch techniques, and hybrid strategies for future optimization.

April 16, 2025

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Perfusion News

Neutrophil Percentage to Albumin Ratio Is Associated With In-Hospital Mortality in Patients With Acute Type A Aortic Dissection

Evaluation of Intraoperative and Postoperative Blood Cell Salvage Use in Cardiac Surgery with Cardiopulmonary Bypass

Comparative Efficacy of Blood Salvage Techniques After Cardiopulmonary Bypass: Centrifugation, Modified Ultrafiltration, and Hemobag Systems in Adult Cardiac Surgery

Outcomes of a Standardized Protocol on the Management of Acute Type A Aortic Dissection: A Retrospective Cohort Study

Clinical and Preclinical Evidence on a Novel Percutaneous Pulsatile Ventricular Assist Device (PulseCath): Protocol for a Scoping Review

Del Nido Cardioplegia in Adult Cardiac Surgery: A Narrative Review

Revolutionizing Cardiovascular Interventions With Artificial Intelligence

Predictors of Prolonged Intensive Care Unit Stay and In-Hospital Mortality Following Cardiac Surgery: An Integrated Analysis from the PROCARD-ATI Study

Impact of Prolonged Cardiopulmonary Bypass on Gastrointestinal Complications in Cardiac Surgery: A Retrospective Cohort Study

The Past, Present, and Future of Off-Pump Coronary Artery Bypass Grafting

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