The Multifactorial Dynamic Perfusion Index: A Predictive Tool of Cardiac Surgery Associated Acute Kidney Injury

January 27, 2024 No Comments

This study aimed to develop a dynamic predictive model for cardiac surgery associated acute kidney injury (CSA-AKI) by combining preoperative and intraoperative risk factors, including cardiopulmonary bypass (CPB) related data. The resulting Multifactorial Dynamic Perfusion Index (MDPI) demonstrated better predictive ability than static risk models, showing that inclusion of dynamic CPB quality indices significantly improves risk assessment for CSA-AKI.

Efficacy of Electroacupuncture on Myocardial Protection and Postoperative Rehabilitation in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass: A Systematic Review and Meta-Analysis

January 26, 2024 No Comments

This study evaluated the efficacy of electroacupuncture (EA) in myocardial protection and postoperative rehabilitation in patients undergoing cardiac surgery with cardiopulmonary bypass, using data from fourteen randomized controlled trials involving 836 patients. The results suggest that EA may reduce myocardial ischaemia-reperfusion injury and enhance postoperative recovery, with no reported adverse reactions, although the findings are based on evidence of mostly low or moderate quality, indicating a need for more high-quality, large-scale studies.

Timing of Chest Tube Removal Following Adult Cardiac Surgery: A Cluster Randomized Controlled Trial

January 26, 2024 No Comments

This study compared two fast-track chest tube removal protocols in cardiac surgery patients, focusing on risks of pleural or pericardial effusions, opioid requirements, respiratory function, and postoperative complications. Results showed that early chest tube removal did not significantly reduce analgesic needs, improve respiratory function, or decrease postoperative complications, and was associated with a high rate of pleural effusions, leading to the study’s early termination for futility.

Safety-Net Hospital Status Is Associated With Coronary Artery Bypass Grafting Outcomes at an Urban Academic Medical Center

January 26, 2024 No Comments

The study investigated the impact of socioeconomic factors and referral status from a county hospital (CH) on outcomes of coronary artery bypass grafting (CABG). It found that patients from CH had greater comorbidities, more often required nonelective surgery, and faced a significantly higher risk of major adverse cardiovascular events (MACE) postoperatively.

The Anti-Apoptotic Effect of Ranolazine on Cerebral Protection during Cardiopulmonary Bypass and Carotid Artery Surgery

January 25, 2024 No Comments

This study investigated the neuroprotective effects of ranolazine (Rn) in a rat model of cerebral ischemia induced by carotid artery clamping. Results showed that Rn-treated groups had significant changes in various biochemical markers, indicating an antiapoptotic effect of Rn in brain ischemia-reperfusion, suggesting its potential usability in cardiac surgeries and carotid artery interventions.

GPT Serum CIRP Increases the Risk of Acute Kidney Injury After Cardiac Surgery

January 25, 2024 No Comments

This study explored the connection between elevated Cold-induced RNA-binding protein (CIRP) levels and the incidence of acute kidney injury (AKI) following cardiac surgery, focusing on surgeries involving cardiopulmonary bypass (CPB). It was discovered that higher CIRP levels, especially in surgeries with CPB, are independently associated with a higher risk of developing AKI, leading to worse postoperative outcomes, including a lower survival rate over two years.

Retrograde Type A Acute Aortic Dissection With Cerebral Malperfusion Six Years After Thoracic Endovascular Aortic Repair

January 24, 2024 No Comments

A 59-year-old male, previously treated with thoracic endovascular aortic repair (TEVAR), developed retrograde type A aortic dissection, leading to cerebral infarction and carotid artery occlusion. He underwent successful total arch replacement and carotid artery bypass, followed by rehabilitation, highlighting the complex challenges and critical interventions needed for TEVAR complications.

Surgical Management and Outcomes of Coronary Artery Involvement Secondary to Acute Type A Aortic Dissection: A Retrospective Cohort Study

January 23, 2024 No Comments

In a study of patients with acute type A aortic dissection (ATAAD) undergoing total arch replacement (TAR) and frozen elephant trunk (FET) implantation, it was found that those with coronary artery involvement (CAI) experienced more complicated surgeries, longer hospital stays, and higher rates of in-hospital morbidity and mortality compared to those without CAI. Although coronary artery malperfusion (CAM) due to CAI was an independent risk factor for in-hospital mortality, short-term survival post-discharge was similar between patients with and without CAI.

Cardiac Rehabilitation and Acute Aortic Dissection: Understanding and Addressing the Evidence GAP A Systematic Review

January 23, 2024 No Comments

Despite established guidelines, there’s a lack of concrete strategies for implementing cardiac rehabilitation (CR) in patients with acute aortic dissection (AAD), particularly regarding how to adapt guidelines for different patient variables. A systematic review covering 2004-2023 found limited evidence but generally positive outcomes from CR in AAD patients, with improvements in exercise capacity and quality of life, suggesting the need for a well-designed trial to explore CR’s benefits in this high-risk group.

Mediation of Age and Thrombectomy Outcome by Neuroimaging Markers of Frailty in Patients With Stroke

January 23, 2024 No Comments

This study explored how age impacts the functional outcome in patients with acute ischemic stroke who received endovascular thrombectomy (EVT), and found that the association between age and 90-day outcome was largely mediated by neuroimaging markers of frailty, such as brain atrophy and small vessel disease, highlighting the significance of these features beyond chronological age in predicting poststroke outcomes. The study suggests that future trials could consider incorporating frailty markers to better assess and adjust for poststroke outcomes.