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TAVR 2024

Long-Term Impact of Cardiac Damage Following Transcatheter Aortic Valve Replacement

This study explores the prognostic implications of changes in cardiac damage following transcatheter aortic valve replacement (TAVR). Analyzing 1,863 patients from the SwissTAVI Registry, researchers found significant variations in cardiac damage stages pre- and post-TAVR, affecting long-term survival. Nearly half of the patients experienced changes in cardiac stage, highlighting the importance of cardiac damage evaluation for predicting outcomes after TAVR.

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April 30, 2024
Duck Injection

Injection Site Matters: A Comparative Analysis of Transpulmonary Thermodilution via Simultaneous Femoral and Jugular Indicator Injections under Veno-Venous Extracorporeal Membrane Oxygenation Therapy

This study assesses how injection sites affect hemodynamic monitoring in patients on vv-ECMO therapy using the PiCCO system. By comparing simultaneous jugular and femoral indicator injections, it was found that femoral injections overestimate key parameters like EVLWI, ITBVI, and GEDVI. The discrepancies are linked to variations in the mean transit time and downslope time, correlated with extracorporeal blood flow, suggesting the injection site significantly impacts measurement accuracy.

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April 30, 2024
Goal Directed Perfusion

Intraoperative Goal-Directed Perfusion in Cardiac Surgery with Cardiopulmonary Bypass: The Roles of Delivery Oxygen Index and Cardiac Index

This study explores the efficacy of intraoperative Goal-Directed Perfusion (GDP) in reducing postoperative complications, ICU, and hospital stay durations in cardiac surgery using cardiopulmonary bypass. By monitoring and optimizing oxygen delivery and cardiac index, GDP significantly lowered ICU stays and hospital lengths of stay, although it did not significantly affect mortality rates.

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April 30, 2024
ECMO 45

Mid-Term Outcome after Extracorporeal Life Support in Postcardiotomy Cardiogenic Shock: Recovery and Quality of Life

This study evaluates the mid-term outcomes of extracorporeal life support (ECLS) in patients with refractory postcardiotomy cardiogenic shock, identifying factors like preoperative EuroSCORE II, renal function, cardiopulmonary bypass duration, and lactate levels as predictors of mortality. Survival rates and health-related quality of life (HRQoL) were assessed, showing acceptable results in surviving patients with a considerable percentage free from moderate to severe disability.

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April 29, 2024
DRESS

Heparin-Induced DRESS Syndrome in a Pediatric Patient and Successful Anaesthetic Management in Cardiovascular Bypass Surgery: Case Report

This case report discusses a pediatric patient with heparin-induced DRESS Syndrome managed successfully during cardiovascular bypass surgery. An 11-year-old with native aortic valve endocarditis developed DRESS after receiving unfractionated heparin. The syndrome, characterized by fever, eosinophilia, and a pruritic rash, was initially managed with corticosteroids. A subsequent episode prompted a shift to bivalirudin and fondaparinux, avoiding further complications and stabilizing the patient’s condition. This case emphasizes the need for alternative anticoagulation strategies in hypersensitive patients to improve outcomes.

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April 28, 2024
ECMO AI

Machine Learning Based Predictive Modeling of Readmissions Following Extracorporeal Membrane Oxygenation Hospitalizations

This study developed and assessed machine learning models, particularly using XGBoost, to predict 90-day nonelective readmissions following extracorporeal membrane oxygenation (ECMO) hospitalizations. Analyzing data from the Nationwide Readmissions Database (2016-2020), the study found that the XGBoost model outperformed traditional logistic regression in prediction accuracy and calibration. Key factors influencing readmission rates included duration of hospital stay, heart/lung transplants, and type of insurance.

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April 28, 2024
Ischemic Heart

Remote Ischemic Preconditioning and Cognitive Dysfunction Following Coronary Artery Bypass Grafting: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

This systematic review and meta-analysis evaluates the effectiveness of remote ischemic preconditioning (RIPC) in preventing cognitive dysfunction after coronary artery bypass grafting (CABG) with cardiopulmonary bypass. Despite hypothesized benefits, the meta-analysis of five studies encompassing 1,843 participants showed that RIPC does not significantly reduce the incidence or severity of postoperative cognitive dysfunction. The findings suggest that RIPC is not effective as a neuroprotective strategy in CABG patients.

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April 27, 2024
Cyber Security

LivaNova Reports Cyberattack Compromising US Patients’ Data

LivaNova, a medical technology company, has reported a cyberattack on its U.S. subsidiary, compromising personal data of its patients. Detected on November 19, 2023, the breach involved unauthorized access to data including Social Security numbers, medical details, and contact information. The company has taken remedial action, offered identity protection services, and advises affected individuals to monitor their accounts and credit reports for fraud.

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April 26, 2024
Predication Models

A Systematic Review of Cardiac Surgery Clinical Prediction Models That Include Intra-operative Variables

This systematic review assesses clinical prediction models (CPMs) that incorporate intra-operative variables to predict outcomes following adult cardiac surgery. It highlights the identification of 24 CPMs, predominantly predicting acute kidney injury and peri-operative mortality, using common variables like cardiopulmonary bypass time. Despite acceptable discrimination in internally validated models, poor calibration and high bias risk limit their practical use. The review suggests potential improvement in model accuracy with intra-operative data, advocating for more robust studies.

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April 26, 2024
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