
Cell Therapies During Machine Perfusion: Promise and the Transplant Gap
A systematic review of 31 studies examines cell and extracellular-vesicle therapies during organ perfusion, highlighting the gap between biomarkers and transplant function.
Explore articles, research, and perspectives from the International Perfusion Association.

A systematic review of 31 studies examines cell and extracellular-vesicle therapies during organ perfusion, highlighting the gap between biomarkers and transplant function.

A UK case report describes a 36-year-old woman with fulminant myocarditis who survived refractory cardiac arrest after ECPR, central biventricular assist-device support, and subsequent

A 23-month-old donor supported on VA-ECMO provided a liver recovered using normothermic regional perfusion. The graft went to a child with maple syrup urine

A Vanderbilt case report describes parallel VV–VA ECMO with axillary Impella 5.5 as a bridge to heart–lung transplantation in a 65-year-old man with severe

In a randomized trial of 60 valve-surgery patients, adenosine added to terminal warm-blood aortic root reperfusion was associated with more intraoperative defibrillation and antiarrhythmic

An updated review of 20 observational studies links normothermic regional perfusion to fewer ischemic biliary complications after controlled DCD liver transplantation. Ischemic cholangiopathy risk

A retrospective review of 75 abdominal NRP procedures compared intra-abdominal with descending thoracic cannulation. Thoracic access was associated with shorter cannulation time, higher circuit

This single-center retrospective study of 381 adult heart transplants found that prolonged oxygen extraction ratio, or O2ER, above 0.20 during cardiopulmonary bypass was linked

This case report describes the first known heart-liver-kidney transplant for AL amyloidosis using organs recovered from a donation-after-circulatory-death donor with thoracoabdominal normothermic regional perfusion.

This institutional retrospective study evaluated 72 patients bridged to heart transplant with the Impella 5.5 and compared outcomes for support durations of 14 days

This nationwide propensity-matched study of 7.5 million U.S. heart failure hospitalizations (2016–2022) found that urban teaching hospitals had higher inpatient mortality, complication rates, length

This large UNOS registry study of 8,489 DCD liver transplants (2010–2024) found that shorter donor time to death (TTD) was associated with worse graft
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