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International
Perfusion Association

Tranexamic Acid

Explore articles, research, and perspectives from the International Perfusion Association.

Topical Use of Tranexamic Acid for Antifibrinolysis in Cardiac Surgery With Cardiopulmonary Bypass: A Randomized Clinical Study

This randomized trial compared topical intrapericardial tranexamic acid (TXA) with standard intravenous TXA in 492 adults undergoing cardiac surgery with cardiopulmonary bypass. Topical TXA

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May 5, 2026

Tranexamic Acid Does Not Have a Dose-Dependent Effect on Postoperative Delirium After Cardiac Surgery — A Retrospective Cohort Study

This retrospective study examined over 5,500 patients undergoing cardiac surgery to assess whether higher doses of tranexamic acid (TXA) reduce postoperative delirium (PD). Despite

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Jan 28, 2026

Efficacy of Goal-Directed Versus Preemptive Tranexamic Acid Administration in Cardiovascular Surgery: The GDT Trial

The GDT trial compares goal-directed tranexamic acid (TXA) administration guided by rotational thromboelastometry (ROTEM) to preemptive TXA administration in cardiovascular surgery. This multi-center, double-blind,

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Dec 4, 2024

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