Explore articles, research, and perspectives from the International Perfusion Association.
A meta-analysis of seven randomized trials examines goal-directed perfusion, oxygen delivery, and cardiac index, with benefits for recovery and important evidence limitations.
A study combines clinical prediction models with experimental evidence linking lactate metabolism and kidney injury after CPB. Clinical treatment benefit remains unproven.
A scoping review maps 20 comparative studies of ECMO–RRT configurations. Findings on filter life, pressure alarms, and delivered therapy remain heterogeneous, with no consistently
WEANILEVO randomized 80 adults ready for VA-ECMO weaning to levosimendan or placebo. Weaning failure occurred in 25% of both groups. Levosimendan was associated with
A double-blinded multicenter trial found significantly more acute kidney injury with dextran versus crystalloid priming during cardiopulmonary bypass (81% vs 53%), despite reduced hemolysis.
A prospective study of 100 adults found that cardiopulmonary bypass lasting more than 120 minutes was associated with higher early postoperative acute kidney injury
This systematic review and meta-analysis evaluated whether hyperoncotic 20%–25% human albumin affects acute kidney injury after adult on-pump cardiac surgery. Across four studies including
This retrospective Malaysian cohort study examined 6,779 adult cardiac surgery patients and found that 4.5% developed postoperative acute kidney injury requiring dialysis. Risk was
This study examines whether hemolysis, measured by cell-free hemoglobin (CFHb), predicts acute kidney injury (AKI) after cardiac surgery in patients with preexisting renal dysfunction.
This study evaluates a machine learning (ML) model using electronic health record (EHR) data to predict acute kidney injury (AKI) after cardiac surgery. In
This meta-analysis of 12 studies (908 patients) compares 6% hydroxyethyl starch (HES 130/0.4) and 5% albumin in cardiac surgery with cardiopulmonary bypass. Results show
This scoping review evaluates the association between central venous pressure (CVP) and acute kidney injury (AKI) following cardiac surgery, particularly CABG. Across 16 studies,
