Heparin-Induced DRESS Syndrome in a Pediatric Patient and Successful Anaesthetic Management in Cardiovascular Bypass Surgery: Case Report

April 28, 2024 No Comments

This case report discusses a pediatric patient with heparin-induced DRESS Syndrome managed successfully during cardiovascular bypass surgery. An 11-year-old with native aortic valve endocarditis developed DRESS after receiving unfractionated heparin. The syndrome, characterized by fever, eosinophilia, and a pruritic rash, was initially managed with corticosteroids. A subsequent episode prompted a shift to bivalirudin and fondaparinux, avoiding further complications and stabilizing the patient’s condition. This case emphasizes the need for alternative anticoagulation strategies in hypersensitive patients to improve outcomes.

Effect of Geography on the Use of Ultrafiltration During Cardiac Surgery with Cardiopulmonary Bypass

April 22, 2024 No Comments

This study explores geographic differences in ultrafiltration (UF) use during cardiopulmonary bypass in the US, analyzing data from 92,859 cardiac surgeries across four regions. Results reveal significant regional disparities in UF usage and volumes, with the Northeast and West employing UF more frequently than the Midwest and South. Variations were also noted in intraoperative urine output and red blood cell transfusion rates, prompting calls for further research into the causes of these differences.

Risk Prediction Models for Renal Function Decline After Cardiac Surgery Within Different Preoperative Glomerular Filtration Rate Strata

April 21, 2024 No Comments

This study focuses on developing risk prediction models to identify patients at risk of renal function decline post-cardiac surgery. Using data from 24,904 patients at Fuwai Hospital, the study found significant variances in renal decline risks across different preoperative glomerular filtration rate (eGFR) strata. Notably, patients with higher eGFR levels pre-surgery showed increased risk. The research produced distinct nomograms for each eGFR category, demonstrating good predictive accuracy and providing a practical tool for postoperative renal monitoring.

Methodologic Quality and Pharmacotherapy Recommendations for Patient Blood Management Guidelines for Cardiac Surgery on Cardiopulmonary Bypass

April 21, 2024 No Comments

This study evaluates the methodological quality and pharmacotherapy recommendations of Patient Blood Management (PBM) guidelines for cardiac surgery involving cardiopulmonary bypass (CPB). Analyzing guidelines using the AGREE II tool, it highlights varying consistency across documents, especially in stakeholder involvement. The study reviews drug therapy strategies including anemia therapy, perioperative antithrombotic administration, intraoperative anticoagulation, and hemostatic drug use, noting a lack of pediatric-specific evidence and the cautious use of certain drugs post-surgery.

Impact of Postoperative Cerebral Complications in Acute Infective Endocarditis: A Retrospective Single-Center Study

April 21, 2024 No Comments

This retrospective study at a single center explored the impact of preoperative cerebral complications on patients with acute infective endocarditis (IE). Among 31 patients analyzed, those with intracranial findings prior to surgery did not experience a worse postoperative course despite being older and having more complex clinical profiles. Notably, one patient without previous cerebral issues developed a cerebral hemorrhage postoperatively, highlighting the need for careful monitoring and preventative strategies for all IE patients, regardless of initial cerebral status.

Comparison of Del Nido Cardioplegia and Crystalloid Blood Cardioplegia on Arrhythmia and Early Results

April 21, 2024 No Comments

This study compares the efficacy of Del Nido cardioplegia (DN) and traditional crystalloid blood cardioplegia in patients undergoing coronary artery bypass surgery, focusing on their effects on arrhythmias and early surgical outcomes. The research involved 175 patients using crystalloid cardioplegia and 150 patients using DN solution. Findings suggest that DN solution, particularly when part of the dose is administered through grafts, leads to better control of arrhythmias post-surgery, reduced need for pacing, and shorter hospital and intensive care unit stays.

Inflammation in Aortic Surgery: Postoperative Evolution of Biomarkers According to Pathologies and Segments of the Aorta

April 19, 2024 No Comments

This study analyzes the postoperative trends of inflammatory biomarkers in 193 patients who underwent various types of aortic surgery. The research focused on the differing responses across four main surgical interventions: Type A aortic dissection repair, aortic root replacement, combined aortic arch and Frozen elephant trunk procedures, and descending/thoraco-abdominal aortic repair. Findings highlighted that inflammation levels, measured by WBC and CRP, vary significantly depending on the surgery type and aortic segment involved, with some groups showing prolonged inflammation.

The Systemic Immune-Inflammation Index Predicts In-Hospital Mortality in Patients Who Underwent On-Pump Cardiac Surgery

April 19, 2024 No Comments

This study explores the role of the Systemic Immune-Inflammation Index (SII), derived from platelet, neutrophil, and lymphocyte counts, as a predictor of in-hospital mortality for patients undergoing on-pump cardiac surgery. Analyzing data from 480 patients, it was found that a higher preoperative SII is independently associated with an increased risk of mortality. With a sensitivity and specificity of 65%, SII, along with neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR), provides valuable prognostic information, potentially guiding more effective treatments.

The Efficacy of Tranexamic Acid in Reducing Perioperative Drainage in Cardiac Surgery with Cardiopulmonary Bypass

April 17, 2024 No Comments

This study evaluates the effectiveness of tranexamic acid in reducing bleeding during and after cardiac surgery involving cardiopulmonary bypass. It compared 40 patients who received tranexamic acid to 40 who did not, finding significant differences in bleeding and transfusion rates, and improvements in hematological parameters for the treated group. These results suggest tranexamic acid effectively minimizes bleeding in such surgeries.

Advancing Cardiotomy Suction Practices for Coronary Surgery via Multidisciplinary Collaborative Learning

April 12, 2024 No Comments

This study focuses on a multidisciplinary quality-improvement intervention to standardize cardiotomy suction practices at the end of cardiopulmonary bypass during coronary artery bypass grafting. Conducted across 32 centers, the initiative showed significant improvements in adherence to recommended practices in Michigan centers compared to non-participating centers, with no adverse effects on clinical outcomes.

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Heparin-Induced DRESS Syndrome in a Pediatric Patient and Successful Anaesthetic Management in Cardiovascular Bypass Surgery: Case Report

Effect of Geography on the Use of Ultrafiltration During Cardiac Surgery with Cardiopulmonary Bypass

Risk Prediction Models for Renal Function Decline After Cardiac Surgery Within Different Preoperative Glomerular Filtration Rate Strata

Methodologic Quality and Pharmacotherapy Recommendations for Patient Blood Management Guidelines for Cardiac Surgery on Cardiopulmonary Bypass

Impact of Postoperative Cerebral Complications in Acute Infective Endocarditis: A Retrospective Single-Center Study

Comparison of Del Nido Cardioplegia and Crystalloid Blood Cardioplegia on Arrhythmia and Early Results

Inflammation in Aortic Surgery: Postoperative Evolution of Biomarkers According to Pathologies and Segments of the Aorta

The Systemic Immune-Inflammation Index Predicts In-Hospital Mortality in Patients Who Underwent On-Pump Cardiac Surgery

The Efficacy of Tranexamic Acid in Reducing Perioperative Drainage in Cardiac Surgery with Cardiopulmonary Bypass

Advancing Cardiotomy Suction Practices for Coronary Surgery via Multidisciplinary Collaborative Learning

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