Efficacy of Electroacupuncture on Myocardial Protection and Postoperative Rehabilitation in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass: A Systematic Review and Meta-Analysis

January 26, 2024 No Comments

This study evaluated the efficacy of electroacupuncture (EA) in myocardial protection and postoperative rehabilitation in patients undergoing cardiac surgery with cardiopulmonary bypass, using data from fourteen randomized controlled trials involving 836 patients. The results suggest that EA may reduce myocardial ischaemia-reperfusion injury and enhance postoperative recovery, with no reported adverse reactions, although the findings are based on evidence of mostly low or moderate quality, indicating a need for more high-quality, large-scale studies.

The Anti-Apoptotic Effect of Ranolazine on Cerebral Protection during Cardiopulmonary Bypass and Carotid Artery Surgery

January 25, 2024 No Comments

This study investigated the neuroprotective effects of ranolazine (Rn) in a rat model of cerebral ischemia induced by carotid artery clamping. Results showed that Rn-treated groups had significant changes in various biochemical markers, indicating an antiapoptotic effect of Rn in brain ischemia-reperfusion, suggesting its potential usability in cardiac surgeries and carotid artery interventions.

Surgical Management and Outcomes of Coronary Artery Involvement Secondary to Acute Type A Aortic Dissection: A Retrospective Cohort Study

January 23, 2024 No Comments

In a study of patients with acute type A aortic dissection (ATAAD) undergoing total arch replacement (TAR) and frozen elephant trunk (FET) implantation, it was found that those with coronary artery involvement (CAI) experienced more complicated surgeries, longer hospital stays, and higher rates of in-hospital morbidity and mortality compared to those without CAI. Although coronary artery malperfusion (CAM) due to CAI was an independent risk factor for in-hospital mortality, short-term survival post-discharge was similar between patients with and without CAI.

Finding a Common Definition of Heparin Resistance in Adult Cardiac Surgery: Communication from the ISTH SSC Subcommittee on Perioperative and Critical Care Thrombosis and Hemostasis

January 21, 2024 No Comments

Ensuring sufficient anticoagulation in cardiac surgery and cardiopulmonary bypass is crucial for preventing adverse outcomes. This review evaluates various definitions of heparin resistance in this context, proposing a standardized definition based on the inability to achieve an activated clotting time target of 480 or more after a dose of 500 U/kg of heparin.

Risk Factors and Short-Term Outcomes of Postoperative Pulmonary Complications in Elderly Patients After Cardiopulmonary Bypass

January 11, 2024 No Comments

This study on elderly patients undergoing cardiopulmonary bypass (CPB) found a high incidence (56.82%) of postoperative pulmonary complications (PPCs), identifying low serum albumin levels, specific types of surgery, prolonged CPB, blood transfusion, and pre-extubation intra-aortic balloon pump use as significant risk factors. These PPCs led to longer mechanical ventilation, extended hospital and ICU stays, increased mortality, and higher tracheotomy rates, highlighting the importance of recognizing these risk factors for better perioperative prevention in elderly CPB patients.

Prospective Clinical Study Testing the Efficacy and Safety of a New Formula to Increase the Precision of Oxygen Therapy in the Initiation Phase of Cardiopulmonary Bypass

January 7, 2024 No Comments

This study developed a formula for tailored oxygen therapy during cardiopulmonary bypass (CPB) to prevent cellular hypoxia and minimize the risk of hyperoxemia. In a pilot study, the formula aimed for a specific arterial partial oxygen pressure (PaO2) range, but only 38.75% of patients achieved the target range, indicating a need for further adjustments to the formula to enhance its effectiveness in guiding oxygen therapy during CPB.

Simulated Cardiopulmonary Bypass: A High Fidelity Model for Developing and Accessing Clinical Perfusion Skills

January 5, 2024 No Comments

The study describes a simulated cardiopulmonary bypass (CPB) model integrated into a mock operative theater, aiming to enhance the training of novice perfusionists. Results from 81 participants indicated high fidelity and effectiveness of the simulation in replicating real CPB scenarios and skills, suggesting its potential for educational use in clinical perfusion training.

Hemolysis Precedes Urine Color Change in Patients Undergoing Open-Heart Surgery on Cardiopulmonary Bypass

January 5, 2024 No Comments

This study investigated the relationship between plasma free hemoglobin levels and changes in urine color in cardiac surgery patients undergoing cardiopulmonary bypass. It found that changes in urine color or increases in urinary free hemoglobin occurred considerably later than elevations in plasma free hemoglobin levels.

Effects of Blood Transfusion, Cardiopulmonary Bypass Time, and Bypassed Vessels on Mortality Following Isolated and Combined Coronary Artery Bypass Grafting

January 4, 2024 No Comments

This study analyzed 677 patients to investigate the correlation between the number of bypassed vessels, cardiopulmonary bypass duration, blood transfusion requirements, revision rates, and mortality in coronary artery bypass grafting surgeries. Results indicated that higher revision rates were associated with six-vessel bypasses, longer bypass and cross-clamp times, increased blood transfusions, and mortality, with specific blood thinners affecting transfusion needs and mortality outcomes.

The Effect of Perioperative Antithrombin Supplementation on Blood Conservation and Postoperative Complications After Cardiopulmonary Bypass Surgery: A Systematic Review, Meta-Analysis and Trial Sequential Analysis

January 4, 2024 No Comments

This meta-analysis investigated the effect of perioperative antithrombin (AT) supplementation on patients undergoing cardiopulmonary bypass (CPB) surgery, analyzing 13 randomized controlled trials with 996 participants. The study found that perioperative AT did not significantly reduce postoperative blood loss or the need for blood transfusions, and it was associated with increased in-hospital mortality and acute kidney injury incidence.

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Efficacy of Electroacupuncture on Myocardial Protection and Postoperative Rehabilitation in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass: A Systematic Review and Meta-Analysis

The Anti-Apoptotic Effect of Ranolazine on Cerebral Protection during Cardiopulmonary Bypass and Carotid Artery Surgery

Surgical Management and Outcomes of Coronary Artery Involvement Secondary to Acute Type A Aortic Dissection: A Retrospective Cohort Study

Finding a Common Definition of Heparin Resistance in Adult Cardiac Surgery: Communication from the ISTH SSC Subcommittee on Perioperative and Critical Care Thrombosis and Hemostasis

Risk Factors and Short-Term Outcomes of Postoperative Pulmonary Complications in Elderly Patients After Cardiopulmonary Bypass

Prospective Clinical Study Testing the Efficacy and Safety of a New Formula to Increase the Precision of Oxygen Therapy in the Initiation Phase of Cardiopulmonary Bypass

Simulated Cardiopulmonary Bypass: A High Fidelity Model for Developing and Accessing Clinical Perfusion Skills

Hemolysis Precedes Urine Color Change in Patients Undergoing Open-Heart Surgery on Cardiopulmonary Bypass

Effects of Blood Transfusion, Cardiopulmonary Bypass Time, and Bypassed Vessels on Mortality Following Isolated and Combined Coronary Artery Bypass Grafting

The Effect of Perioperative Antithrombin Supplementation on Blood Conservation and Postoperative Complications After Cardiopulmonary Bypass Surgery: A Systematic Review, Meta-Analysis and Trial Sequential Analysis

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