This study compared clinician predictions of survival to hospital discharge versus established ECMO survival prediction scores (RESP and SAVE). Conducted from January 2020 to November 2021, it involved interviews with nurses, perfusionists, and physicians within the first 24 hours of ECMO initiation. Results showed that clinicians, especially perfusionists and physicians, often had more accurate survival predictions than the RESP and SAVE scores. The study highlights the need for improved prediction tools.