This meta-analysis compared the midterm clinical outcomes of reimplantation versus remodeling techniques for valve-sparing aortic root replacement in patients with connective tissue disorders, finding no significant difference in mortality, reoperation rates, or postoperative aortic regurgitation. However, a sensitivity analysis excluding annuloplasty suggested that reimplantation may be superior to remodeling alone, indicating that further research is needed to fully evaluate these surgical techniques in this patient demographic.