International Perfusion Association

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IPA

Day: December 22, 2023

Investigating the Complications and Causes of Failure of the AngioVac System: A Post-Marketing Surveillance From the MAUDE Database

The AngioVac aspiration thrombectomy device, approved for removing thrombi during bypass, has been reported to commonly fail due to physical damage and is associated with adverse events such as pulmonary embolism and vessel perforation, as per data from the Manufacturer and User Facility Device Experience database between April 2013 and March 2022. Physicians should be cognizant of these potential complications and the fact that the device’s most frequent failures are attributed to its physical damage.

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December 22, 2023

Development of New Colloid Osmotic Pressure Measurement Method Using Ultrafiltration Membrane During Cardiopulmonary Bypass

A study developed an ultrafiltration membrane method to measure colloid osmotic pressure (COP) and compared it with colloidal osmometer measurements, finding high accuracy, reproducibility, and positive correlation with existing methods. This new method shows potential for improved COP monitoring in clinical settings, suggesting implications for future research and clinical applications.

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December 22, 2023

Extracorporeal Cardiopulmonary Resuscitation: Lifesaving for the Right Patient, at the Right Time and in the Right Place

Extracorporeal membrane oxygenation (ECMO), a life-saving technology for patients with cardiorespiratory failure unresponsive to standard treatments, has seen increased global use since the H1N1 pandemic in 2009, particularly for adult respiratory and cardiac failures. The most rapid expansion of its use has been in extracorporeal cardiopulmonary resuscitation (ECPR), which serves as a critical intervention in cases of refractory cardiac arrest, maintaining circulation and allowing time for potential reversal of the underlying cause.

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December 22, 2023

Meropenem Extraction by Ex Vivo Extracorporeal Life Support Circuits

The study investigates the impact of ECMO and CRRT circuits on meropenem pharmacokinetics, finding minimal extraction by ECMO components but rapid clearance during CRRT, indicating a need for adjusted meropenem dosing in critically ill patients on these therapies. Meropenem underwent significant degradation/metabolism in physiological conditions, informing clinicians on dosing strategies.

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December 22, 2023

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