International Perfusion Association

Category: Uncategorized

ECMO Setup

Clinical Practice of Pre-Assembling and Storing Extracorporeal Membrane Oxygenation Systems

This study surveyed 44 German ECMO centers to evaluate practices in pre-assembling and storing ECMO systems. Results show 77% of centers have preassembled systems (dry, wet, or with circulation), but only 50% have a standard operating procedure (SOP). Most centers discard wet preassembled systems after 20 days, below the ELSO guideline of 30 days. The study highlights the need for evidence-based SOPs to standardize practices, ensure hygiene, and optimize training for ECMO system preassembly and storage.

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Perfusion AI

Artificial Intelligence in the Hands of Perfusionists: Revolutionizing Cardiopulmonary Bypass

This article explores the transformative potential of artificial intelligence (AI) in cardiopulmonary bypass (CPB) and perfusion. AI enhances decision-making by analyzing patient data, optimizing blood flow and pressure parameters, and providing real-time alerts during surgery. It facilitates personalized care, streamlines routine tasks, and improves patient outcomes, particularly in high-risk groups. As AI evolves, it promises to redefine the role of perfusionists and elevate the standards of care in cardiac surgery.

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MICS Cardioplegia

Optimizing Myocardial Protection in Minimally Invasive Cardiac Surgeries: A Comparative Analysis of Cardioplegia Solutions

This network meta-analysis compared four cardioplegia solutions—del Nido (DN), histidine-tryptophan-ketoglutarate (HTK), blood cardioplegia (BC), and St. Thomas’ (STH)—in minimally invasive cardiac surgeries (MICS). Across 15 studies with 2282 patients, no significant differences in major clinical outcomes were found. DN reduced cardiopulmonary bypass times, while HTK shortened hospital stays. Both DN and HTK were deemed safe and effective for long-lasting myocardial protection in MICS.

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Cerebral 2024

Wavelet and Time-Based Cerebral Autoregulation Analysis Using Diffuse Correlation Spectroscopy on Adults Undergoing Extracorporeal Membrane Oxygenation Therapy

This study examines cerebral autoregulation (CA) in adult patients on extracorporeal membrane oxygenation (ECMO) therapy using diffuse correlation spectroscopy (DCS), a noninvasive approach to monitoring cerebral blood flow. Neurological injuries, common in ECMO patients due to underlying conditions or the therapy itself, can impair CA, potentially worsening brain damage. Using wavelet coherence analysis (WCA), researchers found that DCS-based markers identified significant CA differences in ECMO patients with brain injuries versus those without, highlighting the potential of DCS as a monitoring tool for this population.

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Heart Art

Utility of Heparin-Binding Protein Following Cardiothoracic Surgery Using Cardiopulmonary Bypass

This research evaluates Heparin-Binding Protein (HBP) as a biomarker for detecting postoperative infection in patients undergoing cardiothoracic surgery with cardiopulmonary bypass (CPB). It found that HBP levels, which normalize quickly post-surgery, may indicate early postoperative sepsis. Analyzing 1475 patients, the study identified factors influencing HBP levels and its association with 30-day mortality, suggesting HBP’s potential in improving post-surgical outcomes by enabling timely infection detection.

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