International Perfusion Association

Category: Uncategorized

Cerebral 2024

Wavelet and Time-Based Cerebral Autoregulation Analysis Using Diffuse Correlation Spectroscopy on Adults Undergoing Extracorporeal Membrane Oxygenation Therapy

This study examines cerebral autoregulation (CA) in adult patients on extracorporeal membrane oxygenation (ECMO) therapy using diffuse correlation spectroscopy (DCS), a noninvasive approach to monitoring cerebral blood flow. Neurological injuries, common in ECMO patients due to underlying conditions or the therapy itself, can impair CA, potentially worsening brain damage. Using wavelet coherence analysis (WCA), researchers found that DCS-based markers identified significant CA differences in ECMO patients with brain injuries versus those without, highlighting the potential of DCS as a monitoring tool for this population.

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Heart Art

Utility of Heparin-Binding Protein Following Cardiothoracic Surgery Using Cardiopulmonary Bypass

This research evaluates Heparin-Binding Protein (HBP) as a biomarker for detecting postoperative infection in patients undergoing cardiothoracic surgery with cardiopulmonary bypass (CPB). It found that HBP levels, which normalize quickly post-surgery, may indicate early postoperative sepsis. Analyzing 1475 patients, the study identified factors influencing HBP levels and its association with 30-day mortality, suggesting HBP’s potential in improving post-surgical outcomes by enabling timely infection detection.

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