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Perfusion Association

Vasoplegia

Explore articles, research, and perspectives from the International Perfusion Association.

Conceptual illustration of a dilated blood vessel with extracorporeal equipment in the background

Perioperative Management of Vasoplegic Syndrome in Cardiac Surgery

This narrative review examines vasoplegic syndrome after cardiac surgery, linking inflammation, nitric oxide excess, vasopressin deficiency, and renin–angiotensin dysfunction to loss of vascular tone.

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Oct 19, 2026

Intravenous Lidocaine Infusion During Cardiopulmonary Bypass Cardiac Surgery

Evaluation of the Effect of Intravenous Lidocaine on the Systemic Inflammatory Response Associated With Cardiopulmonary Bypass in Valvular and/or Coronary Cardiac Surgery: Protocol for a Double-Blind Randomized Clinical Trial

This single-center, double-blind randomized clinical trial (LEONARD Trial) evaluates whether intravenous lidocaine reduces systemic inflammation triggered by cardiopulmonary bypass in elective valvular and/or coronary

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Feb 16, 2026

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