Explore articles, research, and perspectives from the International Perfusion Association.
A 76-neonate randomized trial compared initial heparin doses during CPB. Higher initial dosing improved ACT response and a thrombin-generation marker, but clinical benefit and
A matched observational study compares heparin plus antithrombin with bivalirudin in adult ECMO, highlighting associations and important limitations.
This scoping review maps the evidence on ECMO anticoagulation strategies beyond unfractionated heparin. Across 135 included records, direct thrombin inhibitors—especially bivalirudin—were the most studied
This retrospective study investigated whether increased white blood cell (WBC) counts correlate with higher unfractionated heparin (UFH) dosage needs during veno-arterial extracorporeal membrane oxygenation
This study delves into heparin resistance (HR) during cardiopulmonary bypass (CPB) surgeries, analyzing 371 patients to identify contributing factors. HR, defined as the inability
