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International
Perfusion Association

Subzero-Balance Ultrafiltration

Explore articles, research, and perspectives from the International Perfusion Association.

AI-generated conceptual illustration of pediatric bypass ultrafiltration equipment and perfusionist hands.

SBUF-SMUF: On the Path to the Optimum Hemofiltration Technique in Pediatric Cardiopulmonary Bypass: A Randomized Clinical Trial

An assessor-blinded randomized trial of 80 children compared SBUF-SMUF with conventional ultrafiltration during cardiac surgery. The combined technique achieved a more negative crystalloid fluid

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Oct 9, 2026

High-Exchange Ultrafiltration During Pediatric Cardiopulmonary Bypass

High-Exchange Ultrafiltration to Enhance Recovery After Pediatric Cardiac Surgery: The ULTRA Randomized Controlled Trial

The ULTRA randomized controlled trial evaluated whether high-exchange subzero-balance ultrafiltration (H-SBUF) during pediatric cardiopulmonary bypass improves recovery compared with low-exchange SBUF. In 104 children

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Feb 18, 2026