Social:

International
Perfusion Association

Protamine Dosing

Explore articles, research, and perspectives from the International Perfusion Association.

Optimising Protamine Dosing for Heparin Reversal After Cardiopulmonary Bypass: A Population Pharmacokinetic—Pharmacodynamic Study

This prospective study of 68 cardiac surgery patients used pharmacometric modeling to determine optimal protamine dosing for reversing unfractionated heparin after cardiopulmonary bypass. Researchers

Read Article

Feb 15, 2026

Protamine Dosing for Heparin Reversal After Cardiopulmonary Bypass: A Double-Blinded Prospective Randomized Control Trial Comparing Two StrategieS

This study compared two protamine dosing strategies for heparin reversal after cardiopulmonary bypass: a fixed 250-mg dose versus a 1:1 (1 mg:100 U heparin)

Read Article

Nov 24, 2024