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International
Perfusion Association

Protamine Administration

Explore articles, research, and perspectives from the International Perfusion Association.

An In-Vitro Study of the Timing Between Protamine Sulfate Administration and Cardiotomy Suction Termination

This in-vitro study evaluates the optimal timing for discontinuing cardiotomy suction during cardiopulmonary bypass (CPB) when reversing heparin anticoagulation with protamine sulfate. Using porcine

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Jan 28, 2026

On-Pump FIBTEM-A5 Accurately Predicts the A5 Values After Protamine Administration

This study investigates whether on-pump FIBTEM-A5 values measured during cardiopulmonary bypass (CPB) accurately predict post-protamine administration values. Conducted at a single cardiac center, the

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Feb 18, 2025

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