A 76-neonate randomized trial compared initial heparin doses during CPB. Higher initial dosing improved ACT response and a thrombin-generation marker, but clinical benefit and
A 100-patient randomized CABG trial reported lower bleeding and transfusion exposure with ACT-guided heparin and protamine dosing. Small size, no prospective registration and dosing-table
A Europe-wide survey of 114 cardiac surgery centers across 29 countries evaluated current anticoagulation practices during cardiopulmonary bypass. Most centers reported standardized heparin protocols
PerfusionGPT AssistantEducation · Research · Global cardiac care
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