Evaluating the Need for Magnesium Administration Following Cardioplegic Arrest with Del Nido Cardioplegia Solution

March 11, 2025 No Comments

This study evaluates whether magnesium administration is necessary following cardioplegic arrest with del Nido cardioplegia (dNC) solution at Cincinnati Children’s Hospital Medical Center (CCHMC). Analyzing serum magnesium levels in 100 patients, results showed hypermagnesemia in most cases. Given the potential risks of excessive magnesium, findings suggest eliminating routine post-cross-clamp magnesium administration in dNC settings.

The Feasibility of a National Matching Service for Perfusion Education Program Applicants

March 10, 2025 No Comments

As the demand for perfusion education programs (PEPs) grows, many qualified applicants struggle to secure spots due to inconsistent admission processes. This study examines the potential benefits of implementing a national matching service (NMS) for PEP applicants, similar to medical residency matches. By standardizing timelines, eliminating unfair practices, and ensuring efficient applicant-program matching, an NMS could enhance the recruitment process and support the growing need for perfusionists.

Development and Validation of a Checklist for Cardiopulmonary Bypass

March 10, 2025 No Comments

This study focuses on developing and validating a checklist for cardiopulmonary bypass (CPB) to enhance patient safety and reduce adverse events. Using the Delphi method, five expert perfusionists refined an initial 42-item checklist down to 41 crucial elements. The final checklist standardizes CPB procedures, ensuring systematic verification of equipment and protocols. The study highlights the importance of structured guidelines in improving surgical outcomes and preventing errors.

Does Intraoperative Cell-Salvaged Autologous Blood Transfusion in Metastatic Spine Tumour Surgery Impact Clinical Outcomes? A Prospective Clinical Study With 4-Year Follow-Up

March 10, 2025 No Comments

This prospective clinical study evaluates the impact of intraoperative cell-salvaged blood transfusion (SBT) on long-term clinical outcomes in metastatic spine tumour surgery (MSTS). Comparing SBT with allogeneic blood transfusion (ABT) and no transfusion (NBT), the study finds no significant difference in overall survival or tumour progression over four years. The findings support SBT as a viable alternative to ABT, reducing risks and dependency on donor blood.

Microvascular Dysfunction Following Cardioplegic Arrest and Cardiopulmonary Bypass: Impacts of Diabetes and Hypertension

March 10, 2025 No Comments

This review examines microvascular dysfunction following cardioplegic arrest and cardiopulmonary bypass (CP/CPB), with a focus on diabetes and hypertension. It explores endothelial and vasomotor dysfunction, gene/protein expression changes, endothelial adherens junction impairment, and programmed cell death. The study highlights the role of oxidative stress, inflammation, and metabolic disruptions, providing insight into potential pharmacological interventions for improving surgical outcomes.

Effect of Intraoperative Fluid Volume on Postoperative Pulmonary Complications in Thoracic Surgeries: A Systematic Review and Meta-Analysis

March 9, 2025 No Comments

This systematic review and meta-analysis investigates the impact of intraoperative fluid volume on postoperative pulmonary complications (PPCs) in thoracic surgeries. Analyzing 11 studies, the review finds that higher intraoperative fluid infusion is associated with an increased risk of PPCs. A restrictive fluid strategy may be safer, though high heterogeneity and potential biases necessitate further randomized controlled trials to establish definitive recommendations.

A Review of Recent Advances in Anesthetic Drugs for Patients Undergoing Cardiac Surgery

March 8, 2025 No Comments

This review explores recent advancements in anesthetic drugs for cardiac surgery. With no standard protocol for anesthesia in these procedures, the article examines commonly used agents such as opioids (fentanyl, sufentanil, remifentanil), volatile anesthetics, and novel drugs like dexmedetomidine and remimazolam. The study highlights opioid-free anesthesia approaches, innovative drug delivery systems, and enhanced recovery techniques to improve patient outcomes and reduce complications.

The Role of Continuous Monitoring of Venous Drainage Flow and Integrated Oxygen Extraction (ERiO2) via Bilateral Near-Infrared Spectroscopy in Cerebral Perfusion During Aortic Arch Surgery

March 6, 2025 No Comments

This study evaluates the role of continuous monitoring of venous drainage flow and oxygen extraction (ERiO2) using near-infrared spectroscopy (NIRS) in cerebral perfusion during aortic arch surgery. A retrospective review of 10 patients undergoing selective antegrade cerebral perfusion (SACP) found a strong correlation (r = 0.91, p < 0.01) between ERiO2 and NIRS-derived regional oxygen saturation (rSO2). The study suggests that integrated monitoring improves perfusion management and neurological outcomes.

Lethal Myocardial Infarction in a Neonate During Extracorporeal Membrane Oxygenation

March 4, 2025 No Comments

This case study explores a neonate with congenital diaphragmatic hernia (CDH) who experienced a lethal myocardial infarction (MI) while on extracorporeal membrane oxygenation (ECMO). The patient developed a large thrombus extending from the arterial cannula into the left main coronary artery, leading to severe cardiac dysfunction. Despite anticoagulation efforts, the clot progressed, resulting in a fatal outcome. The study highlights the challenges of managing neonatal ECMO and intracardiac thrombosis.

Outcomes and Biochemical Parameters Following Cardiac Surgery: Effects of Transfusion of Residual Blood Using Centrifugation and Multiple-Pass Hemoconcentration

March 4, 2025 No Comments

This study compares centrifugation (CF) and multiple-pass hemoconcentration (MPH) for salvaging residual blood after cardiopulmonary bypass. A randomized trial with 61 patients found that MPH resulted in higher postoperative albumin, total protein, fibrinogen, and platelet levels compared to CF. While CF processed blood faster and cleared heparin more consistently, MPH was associated with lower allogeneic transfusion needs and reduced fluid retention. Overall, MPH demonstrated improved biochemical and clinical outcomes.

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Evaluating the Need for Magnesium Administration Following Cardioplegic Arrest with Del Nido Cardioplegia Solution

The Feasibility of a National Matching Service for Perfusion Education Program Applicants

Development and Validation of a Checklist for Cardiopulmonary Bypass

Does Intraoperative Cell-Salvaged Autologous Blood Transfusion in Metastatic Spine Tumour Surgery Impact Clinical Outcomes? A Prospective Clinical Study With 4-Year Follow-Up

Microvascular Dysfunction Following Cardioplegic Arrest and Cardiopulmonary Bypass: Impacts of Diabetes and Hypertension

Effect of Intraoperative Fluid Volume on Postoperative Pulmonary Complications in Thoracic Surgeries: A Systematic Review and Meta-Analysis

A Review of Recent Advances in Anesthetic Drugs for Patients Undergoing Cardiac Surgery

The Role of Continuous Monitoring of Venous Drainage Flow and Integrated Oxygen Extraction (ERiO2) via Bilateral Near-Infrared Spectroscopy in Cerebral Perfusion During Aortic Arch Surgery

Lethal Myocardial Infarction in a Neonate During Extracorporeal Membrane Oxygenation

Outcomes and Biochemical Parameters Following Cardiac Surgery: Effects of Transfusion of Residual Blood Using Centrifugation and Multiple-Pass Hemoconcentration

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