Development and Validation of a Checklist for Cardiopulmonary Bypass

March 10, 2025 No Comments

This study focuses on developing and validating a checklist for cardiopulmonary bypass (CPB) to enhance patient safety and reduce adverse events. Using the Delphi method, five expert perfusionists refined an initial 42-item checklist down to 41 crucial elements. The final checklist standardizes CPB procedures, ensuring systematic verification of equipment and protocols. The study highlights the importance of structured guidelines in improving surgical outcomes and preventing errors.

PerfusionGPT: The Ultimate AI-Powered Resource for Perfusionists

March 8, 2025 No Comments

PerfusionGPT is an AI-powered chatbot based on Open-AI’s latest models, specifically designed to provide expert knowledge for perfusionists in cardiac surgery. It serves as a critical resource for both clinical decision-making and educational purposes in the field of perfusion.

Perfusion Instability During Hyperthermic Intraperitoneal Chemotherapy: The Utility of a Problem-solving Flowchart

March 6, 2025 No Comments

This study examines perfusion instability (PI) during hyperthermic intraperitoneal chemotherapy (HIPEC), where maintaining proper flow and temperature is crucial. A retrospective review of 208 HIPEC cases found a 10.1% incidence of PI. A step-by-step problem-solving flowchart was implemented, significantly improving perfusion stability. The study concludes that structured interventions can mitigate PI, though further research is needed to refine perfusion techniques.

Vasoplegic Syndrome Following Bypass: A Comprehensive Review of Pathophysiology and Proposed Treatments

March 1, 2025 No Comments

Vasoplegic syndrome (VS) is a severe circulatory condition occurring post-cardiopulmonary bypass (CPB), affecting up to 44% of high-risk patients with mortality rates reaching 50%. It is characterized by profound hypotension, vasopressor resistance, and vascular collapse. The review explores pathophysiology, risk factors, and treatments, including nitric oxide synthase inhibitors (methylene blue, hydroxocobalamin), vasopressors, and fluid management to mitigate complications and improve survival.

2024 EACTS/EACTAIC/EBCP Guidelines on Cardiopulmonary Bypass in Adult Cardiac Surgery

February 16, 2025 No Comments

The 2024 EACTS/EACTAIC/EBCP guidelines provide updated, evidence-based recommendations for cardiopulmonary bypass (CPB) in adult cardiac surgery. They cover advancements in perfusion strategies, organ protection, monitoring techniques, and safety measures. Key updates include AI-driven perfusion, enhanced neuromonitoring, and refined protocols for blood management and CPB separation. These guidelines aim to standardize practices, improve outcomes, and ensure patient safety in modern cardiac surgery.

Innovative Balloon-Inflatable Venous Cannula for Enhanced Cardiopulmonary Bypass in Minimally Invasive Cardiac Surgery

February 9, 2025 No Comments

This study introduces the Aulus venous cannula, a novel device for minimally invasive cardiac surgery (MICS) designed to improve cardiopulmonary bypass (CPB). The cannula features heparin coating and internal balloons for superior and inferior vena cava occlusion, reducing external manipulation. Preclinical tests, including ex-vivo and large animal studies, demonstrated effective anticoagulation, precise positioning, and favorable safety outcomes, highlighting its potential for clinical use.

Trial of Oxygen Delivery on Cardiopulmonary Bypass and Major Clinical Outcomes

January 18, 2025 No Comments

This study investigates the impact of oxygen delivery (DO2) during cardiopulmonary bypass (CPB) on major clinical outcomes in cardiac surgery patients. Maintaining adequate DO2 during

Traditional vs. Modified Ringer Lactate-Based del Nido Cardioplegia: Impacts on Clinical Outcomes in Coronary Artery Bypass Grafting

December 26, 2024 No Comments

This prospective, randomized, and blinded study compared the impacts of traditional Plasma-Lyte A-based del Nido cardioplegia (PL DN) and a modified Ringer’s lactate-based formulation (LR DN) on clinical outcomes in patients undergoing coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB). Results showed that while both formulations had similar effects on several clinical parameters, PL DN offered superior myocardial protection, as indicated by lower postoperative cardiac enzyme levels and reduced need for epinephrine.

A Technique Avoiding Cardioplegia Delivery Complications: A Case Using Systemic Hyperkalemia Cardiopulmonary Bypass Combined with Circulatory Arrest

December 24, 2024 No Comments

This case study details a novel approach to avoid cardioplegia delivery complications during a high-risk redo mitral valve replacement. The 75-year-old patient, with severe mitral regurgitation and mild aortic regurgitation, underwent minimally invasive surgery using systemic hyperkalemia and circulatory arrest. The method eliminated the need for aortic cross-clamping, achieving effective myocardial protection and an uneventful recovery, despite complex surgical challenges.

Failure to Oxygenate During Cardiopulmonary Bypass: Treatment Options and Intervention Algorithm

December 23, 2024 No Comments

This study addresses the critical issue of oxygenator failure during cardiopulmonary bypass (CPB), a rare but high-risk event. It explores protocols and techniques for addressing oxygenator malfunction, including traditional oxygenator change-outs and alternative approaches like arterial and venous piggyback methods. The authors emphasize the need for institutional preparation, including written protocols and routine emergency drills, and propose a venous piggyback technique as a safer first-line response to improve patient outcomes.

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Development and Validation of a Checklist for Cardiopulmonary Bypass

PerfusionGPT: The Ultimate AI-Powered Resource for Perfusionists

Perfusion Instability During Hyperthermic Intraperitoneal Chemotherapy: The Utility of a Problem-solving Flowchart

Vasoplegic Syndrome Following Bypass: A Comprehensive Review of Pathophysiology and Proposed Treatments

2024 EACTS/EACTAIC/EBCP Guidelines on Cardiopulmonary Bypass in Adult Cardiac Surgery

Innovative Balloon-Inflatable Venous Cannula for Enhanced Cardiopulmonary Bypass in Minimally Invasive Cardiac Surgery

Trial of Oxygen Delivery on Cardiopulmonary Bypass and Major Clinical Outcomes

Traditional vs. Modified Ringer Lactate-Based del Nido Cardioplegia: Impacts on Clinical Outcomes in Coronary Artery Bypass Grafting

A Technique Avoiding Cardioplegia Delivery Complications: A Case Using Systemic Hyperkalemia Cardiopulmonary Bypass Combined with Circulatory Arrest

Failure to Oxygenate During Cardiopulmonary Bypass: Treatment Options and Intervention Algorithm

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