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Risk and Predictability for Renal Replacement Therapy in Patients Receiving Mechanical Circulatory Support

Limiting the Gamble: Risk and Predictability for Renal Replacement Therapy in Patients Receiving Mechanical Circulatory Support

March 11, 2025 No Comments

This study investigates risk factors for renal replacement therapy (RRT) in patients receiving mechanical circulatory support (MCS). A retrospective analysis of 129 patients revealed an RRT incidence of 36%. Key risk factors include prior immunologic therapy and the presence of pacemakers or internal cardiac defibrillators. Unfractionated heparin showed minimal protection against RRT. Findings suggest systemic inflammation plays a role, emphasizing the need for alternative anticoagulation strategies.

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Evaluating the Need for Magnesium Administration Following Cardioplegic Arrest with Del Nido Cardioplegia Solution

Evaluating the Need for Magnesium Administration Following Cardioplegic Arrest with Del Nido Cardioplegia Solution

March 11, 2025 No Comments

This study evaluates whether magnesium administration is necessary following cardioplegic arrest with del Nido cardioplegia (dNC) solution at Cincinnati Children’s Hospital Medical Center (CCHMC). Analyzing serum magnesium levels in 100 patients, results showed hypermagnesemia in most cases. Given the potential risks of excessive magnesium, findings suggest eliminating routine post-cross-clamp magnesium administration in dNC settings.

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National Matching Service for Perfusion Education Program Applicants

The Feasibility of a National Matching Service for Perfusion Education Program Applicants

March 10, 2025 No Comments

As the demand for perfusion education programs (PEPs) grows, many qualified applicants struggle to secure spots due to inconsistent admission processes. This study examines the potential benefits of implementing a national matching service (NMS) for PEP applicants, similar to medical residency matches. By standardizing timelines, eliminating unfair practices, and ensuring efficient applicant-program matching, an NMS could enhance the recruitment process and support the growing need for perfusionists.

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Development and Validation of a Checklist for Cardiopulmonary Bypass

Development and Validation of a Checklist for Cardiopulmonary Bypass

March 10, 2025 No Comments

This study focuses on developing and validating a checklist for cardiopulmonary bypass (CPB) to enhance patient safety and reduce adverse events. Using the Delphi method, five expert perfusionists refined an initial 42-item checklist down to 41 crucial elements. The final checklist standardizes CPB procedures, ensuring systematic verification of equipment and protocols. The study highlights the importance of structured guidelines in improving surgical outcomes and preventing errors.

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Perfusion Instability During Hyperthermic Intraperitoneal Chemotherapy: The Utility of a Problem-solving Flowchart

Perfusion Instability During Hyperthermic Intraperitoneal Chemotherapy: The Utility of a Problem-solving Flowchart

March 6, 2025 No Comments

This study examines perfusion instability (PI) during hyperthermic intraperitoneal chemotherapy (HIPEC), where maintaining proper flow and temperature is crucial. A retrospective review of 208 HIPEC cases found a 10.1% incidence of PI. A step-by-step problem-solving flowchart was implemented, significantly improving perfusion stability. The study concludes that structured interventions can mitigate PI, though further research is needed to refine perfusion techniques.

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Vasoplegic Syndrome Following Bypass: A Comprehensive Review of Pathophysiology and Proposed Treatments

March 1, 2025 No Comments

Vasoplegic syndrome (VS) is a severe circulatory condition occurring post-cardiopulmonary bypass (CPB), affecting up to 44% of high-risk patients with mortality rates reaching 50%. It is characterized by profound hypotension, vasopressor resistance, and vascular collapse. The review explores pathophysiology, risk factors, and treatments, including nitric oxide synthase inhibitors (methylene blue, hydroxocobalamin), vasopressors, and fluid management to mitigate complications and improve survival.

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EBCP 2024 Guidelines

2024 EACTS/EACTAIC/EBCP Guidelines on Cardiopulmonary Bypass in Adult Cardiac Surgery

February 16, 2025 No Comments

The 2024 EACTS/EACTAIC/EBCP guidelines provide updated, evidence-based recommendations for cardiopulmonary bypass (CPB) in adult cardiac surgery. They cover advancements in perfusion strategies, organ protection, monitoring techniques, and safety measures. Key updates include AI-driven perfusion, enhanced neuromonitoring, and refined protocols for blood management and CPB separation. These guidelines aim to standardize practices, improve outcomes, and ensure patient safety in modern cardiac surgery.

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Balloon IABP

Innovative Balloon-Inflatable Venous Cannula for Enhanced Cardiopulmonary Bypass in Minimally Invasive Cardiac Surgery

February 9, 2025 No Comments

This study introduces the Aulus venous cannula, a novel device for minimally invasive cardiac surgery (MICS) designed to improve cardiopulmonary bypass (CPB). The cannula features heparin coating and internal balloons for superior and inferior vena cava occlusion, reducing external manipulation. Preclinical tests, including ex-vivo and large animal studies, demonstrated effective anticoagulation, precise positioning, and favorable safety outcomes, highlighting its potential for clinical use.

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