International Perfusion Association

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IPA

Category: ECMO

Hemoperfusion

Efficacy of Adjunct Hemoperfusion Compared to Standard Medical Therapy on 28-Day Mortality in Leptospirosis Patients with Renal Failure and Shock: A Single-Center Randomized Controlled Trial

This study evaluates the impact of hemoperfusion (HP) on 28-day mortality in leptospirosis patients with renal failure and septic shock. A total of 37 patients were randomized to receive either standard medical therapy (SMT) or SMT with HP. The HP group showed a 36.84% risk reduction in 28-day mortality and significant improvements in inflammatory markers, renal function, and pulmonary function. Hemoperfusion was shown to be a safe and effective adjunct therapy, promoting faster recovery and increased survival rates.

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September 29, 2024
Thromboembolic Complications ECMO

Thromboembolic Complications in Continuous Versus Interrupted Anticoagulation During Venovenous Extracorporeal Membrane Oxygenation: A Multicenter Study

This study investigates thromboembolic complications in patients undergoing venovenous extracorporeal membrane oxygenation (ECMO) with continuous versus interrupted anticoagulation. Data from 346 patients across three ECMO centers were analyzed. Results showed no significant difference in thrombotic complications between the groups, although interruptions in anticoagulation were linked to increased thrombotic events as the frequency and duration of interruptions rose.

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September 28, 2024
Special K

Extraction of Ketamine and Dexmedetomidine by Extracorporeal Life Support Circuits

This study investigated the extraction of ketamine and dexmedetomidine by extracorporeal life support (ECLS) circuits such as ECMO and CRRT. Using an ex-vivo system, drug concentrations were measured over time in blood-primed circuits. Results showed significant reductions in drug recovery, with ketamine recovering only 43.8% from ECMO and 3.3% from CRRT after several hours. Dexmedetomidine recovery was similarly reduced, highlighting the need for dosage adjustments during ECLS support.

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September 26, 2024
Pediatric ECMO

Outcomes in Patients Who Received ECMO and/or Volatile Anesthetics as Rescue Therapies for Status Asthmaticus

This study explores the outcomes of pediatric patients with status asthmaticus (SA) who received either inhaled volatile anesthetics (IVA), extracorporeal membrane oxygenation (ECMO), or both as rescue therapies in a PICU setting. Among seven patients, most who received IVA were escalated to ECMO. The results suggest that early ECMO cannulation might be beneficial, though larger studies are needed to form conclusive guidelines for SA management in critically ill children.

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September 21, 2024
ECMO Risk

Risk Factors Associated With Hospital Mortality in Non-Surgical Patients Receiving Extracorporeal Membrane Oxygenation and Continuous Renal Replacement Treatment: A Retrospective Analysis

This study identifies risk factors associated with hospital mortality in non-surgical patients receiving extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT). Using data from December 2013 to April 2023, the analysis revealed that older age, longer duration of CRRT, and CRRT implantation were independent predictors of mortality. A prediction model was developed using these factors, demonstrating good accuracy and clinical utility in estimating patient outcomes.

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September 9, 2024
Brain ECMO

Brain Death Donors on Extracorporeal Membrane Oxygenation Support

This study examines 15 brain death donors on extracorporeal membrane oxygenation (ECMO) support, admitted to a specialized intensive care unit between 2018 and 2023. The study evaluates the effect of a strict hemodynamic monitoring schedule during a 6-hour observation period on the utilization rate of organs. Results show an increase in utilization rates from 78% to 88% with no significant differences in donor characteristics or hemodynamic data between periods. Most donors required multiple vasoactive drugs to maintain adequate perfusion.

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September 1, 2024
ECMO Clock

Risk Factors for Mortality in Patients Receiving Extracorporeal Membrane Oxygenation

This study retrospectively analyzes the clinical data of 199 patients who received extracorporeal membrane oxygenation (ECMO) support from 2013 to 2023, revealing a mortality rate of 76.38%. The study identifies continuous renal replacement therapy (CRRT) implantation and age as independent risk factors for mortality in ECMO patients. Additionally, in those receiving combined CRRT and ECMO, the absence of congenital heart disease and a lack of surgical history are also significant mortality risk factors.

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September 1, 2024

Top 5 Reasons to Obtain an IBBM Certification in Blood Management and ECMO

In the competitive healthcare industry, certification in blood management or ECMO through the AmSECT International Board of Blood Management (IBBM) can significantly elevate your career. Certification demonstrates leadership, earns respect from peers, sharpens your skills, enhances career opportunities, and boosts earning potential. Specialized certifications such as PBMT, PBMS, CES-A, and CES-P mark you as a committed expert in patient care.

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August 24, 2024
ECMO 2024

Risk Factors for Elective and Emergency Oxygenator Exchanges During Veno-Venous Extracorporeal Membrane Oxygenation

This observational cohort study explores the risk factors associated with elective and emergency oxygenator exchanges during veno-venous extracorporeal membrane oxygenation (V-V ECMO). Analyzing 45 patients, the study found that higher levels of partial pressure of carbon dioxide (PaCO2), transmembrane pressure difference (ΔP), and hemoglobin (Hb) were significant predictors for an oxygenator exchange, while lower lactate dehydrogenase (LDH) was linked to the risk of an emergency exchange. These findings highlight the need for careful monitoring and timely decision-making in ECMO management to minimize complications.

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August 20, 2024
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