Explore articles, research, and perspectives from the International Perfusion Association.
A matched observational study compares heparin plus antithrombin with bivalirudin in adult ECMO, highlighting associations and important limitations.
An INCEPTION trial-based model projected ECPR costs and quality-adjusted survival over 20 years. The reported ICER was €242,122 per QALY, with a 46% probability
A secondary ECSTATIC analysis examined 161 platelet transfusions in 27 children on ECMO. The median platelet increment was 19 × 10⁹/L. Pathogen-reduced products were
WEANILEVO randomized 80 adults ready for VA-ECMO weaning to levosimendan or placebo. Weaning failure occurred in 25% of both groups. Levosimendan was associated with
The ELIEO multicenter trial will randomize 508 adults with severe ARDS to early vvECMO or conventional care with rescue ECMO. This 2026 paper reports
The X-COPD trial tested extracorporeal CO2 removal in COPD patients requiring invasive ventilation. Recruitment stopped at 18 of 192 planned patients. Ventilation duration was
A national survey of 42 German ECMO centers without perfusionist support found marked variation in ECPR readiness. Centers performing ECPR reported shorter circuit setup
Extracorporeal cardiopulmonary resuscitation (ECPR) can achieve survival approaching 30% for selected patients with refractory out-of-hospital cardiac arrest, but success depends on the entire system
This case report describes a 69-year-old woman who developed thrombotic obstruction of a mitral bioprosthesis while receiving VA-ECMO with left ventricular venting after complex
This cross-sectional study examined 137 ICU nurses in Turkey who cared for patients receiving ECMO, a complex life-support therapy. Nurses reported mild-to-moderate anxiety, with
This guideline article argues that extracorporeal life support device testing should follow standardized in-vitro protocols so results can be reproduced, compared across research groups,
This scoping review maps the evidence on ECMO anticoagulation strategies beyond unfractionated heparin. Across 135 included records, direct thrombin inhibitors—especially bivalirudin—were the most studied
