Malignancy-Induced Functional Tricuspid Obstruction Complicated by Cardiopulmonary Collapse Treated Using Combination VA-ECMO and AngioVac

April 12, 2025 No Comments

This clinical case report details the rescue of a critically ill patient with malignancy-induced tricuspid obstruction and cardiopulmonary collapse. A large intracardiac mass was removed using vacuum-assisted aspiration thrombectomy (AngioVac), combined with venoarterial extracorporeal membrane oxygenation (VA-ECMO). This approach enabled hemodynamic stabilization and definitive diagnosis of diffuse large B-cell lymphoma, followed by successful oncologic treatment.

Multicentre Comparison of Various Microaxial Pump Devices as a Bridge to Durable Assist Device Implantation

April 4, 2025 No Comments

This multicentre retrospective study evaluated the effectiveness of different microaxial flow pump (mAFP) devices—mainly Impella CP (3.5 L/min) and Impella 5+ (>5 L/min)—used to stabilize patients with severe heart failure before durable LVAD implantation. High-flow mAFPs were associated with improved hemodynamic support, reduced complications (e.g., renal/liver failure, RVAD use), and better mobilization, although 30-day mortality did not differ significantly between groups.

On MANTA Vascular Closure Devices Following Veno-Arterial Extracorporeal Membrane Oxygenation: Effectiveness and Complications

April 2, 2025 No Comments

The article explores the safety and effectiveness of the MANTA vascular closure device for managing large-bore arteriotomy, particularly post-decannulation in veno-arterial extracorporeal membrane oxygenation (VA-ECMO) patients. Findings suggest the MANTA device reduces vascular complications and offers a viable, low-risk option for critically ill patients, though further high-powered studies are needed to confirm superiority over other closure methods.

Development of a CO₂ Sensor for Extracorporeal Life Support Applications

March 30, 2025 No Comments

This study presents the development of a novel optical CO₂ sensor for use in extracorporeal life support (ECLS) systems such as ECMO and ECCO₂R. The sensor accurately measures CO₂ concentration in oxygenator exhaust gas and gas flow to determine CO₂ removal rates. A built-in heating system prevents condensation, and a temperature control algorithm ensures measurement accuracy. Laboratory and in vivo validations confirm its clinical suitability.

Impact of Extracorporeal Life Support on Outcome in Patients with Idiopathic Pulmonary Arterial Hypertension Awaiting Lung Transplantation

March 19, 2025 No Comments

This study evaluates the impact of extracorporeal life support (ECLS) as a bridge to lung transplantation (BTT) for patients with idiopathic pulmonary arterial hypertension (iPAH). A comparison between two cohorts (1997–2005 and 2006–2010) shows that ECLS significantly reduced waiting list mortality (from 22% to 0%) while slightly increasing ICU stay. The findings suggest that aggressive ECLS management can improve survival rates for iPAH patients awaiting lung transplants.

Staying in Place: In Vitro Comparison of Extracorporeal Membrane Oxygenation Cannula Fixation for Dislodgment Prevention

March 18, 2025 No Comments

This study evaluates the effectiveness of different fixation methods for ECMO cannulas to prevent dislodgment. Using an in vitro porcine skin model, researchers compared traditional sutures with adhesive securement devices. Results showed that adhesive methods, particularly CathGrip, provided superior stability in micro-movements while maintaining comparable fixation strength to sutures. The study suggests that adhesive anchors may offer a viable alternative for improving ECMO cannula security.

Relatively Increased CO2 Delivered to the Brain From the Descending Aorta Leading to an Elevated Respiratory Rate Causing Differential Hypocapnia (RIDDLER or East-West Syndrome): New Pitfalls in Awake Peripheral V-A ECMO

March 16, 2025 No Comments

This article describes a newly recognized physiological phenomenon, RIDDLER (East-West Syndrome), in patients on awake peripheral V-A ECMO. It occurs when CO2-rich blood from the ECMO circuit reaches the brain, triggering an increased respiratory rate despite paradoxically low CO2 levels in the right radial artery. This leads to a cycle of worsening hypercapnia, respiratory distress, and potential neurological injury. Proper CO2 monitoring strategies are needed to prevent mismanagement.

Indications for Extracorporeal Membrane Oxygenation in Older Adult Patients with Accidental Hypothermia and Hemodynamic Instability

March 16, 2025 No Comments

This study analyzes the efficacy of extracorporeal membrane oxygenation (ECMO) in older adults with accidental hypothermia (AH) and hemodynamic instability before cardiac arrest. A post-hoc analysis of the ICE-CRASH study (2019–2022) found no significant survival difference between ECMO and non-ECMO patients at 28 days. ECMO accelerated rewarming but increased bleeding complications. The study concludes ECMO may not benefit this patient group, challenging existing treatment criteria.

Pediatric Cardiac Patients with Pulmonary Hemorrhage Supported on ECMO: An ELSO Registry Study

March 15, 2025 No Comments

This study examines pediatric cardiac patients with pulmonary hemorrhage (PH) supported on extracorporeal membrane oxygenation (ECMO) using data from the ELSO registry (2011–2020). Analyzing 161 cases, the study identifies high-frequency oscillatory ventilation (HFOV) before ECMO cannulation as a key predictor of survival. The absence of hemorrhagic and renal complications also improved outcomes. Findings suggest that optimized pre-ECMO ventilation strategies may enhance survival rates in these high-risk patients.

Prolonged ECMO Support in a Pediatric Patient with Complex Cardiac Conditions During Wartime in Kyiv, Ukraine

March 14, 2025 No Comments

This case report details the prolonged extracorporeal membrane oxygenation (ECMO) support of a 12-year-old girl with severe congenital heart disease and myocarditis in wartime Kyiv. Due to a lack of transplant options and supply shortages, alternative oxygenators were used despite suboptimal long-term performance. The patient underwent 259 days of ECMO support but ultimately succumbed to multi-organ dysfunction. The study highlights the urgent need for medical resource mobilization in conflict zones.

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Malignancy-Induced Functional Tricuspid Obstruction Complicated by Cardiopulmonary Collapse Treated Using Combination VA-ECMO and AngioVac

Multicentre Comparison of Various Microaxial Pump Devices as a Bridge to Durable Assist Device Implantation

On MANTA Vascular Closure Devices Following Veno-Arterial Extracorporeal Membrane Oxygenation: Effectiveness and Complications

Development of a CO₂ Sensor for Extracorporeal Life Support Applications

Impact of Extracorporeal Life Support on Outcome in Patients with Idiopathic Pulmonary Arterial Hypertension Awaiting Lung Transplantation

Staying in Place: In Vitro Comparison of Extracorporeal Membrane Oxygenation Cannula Fixation for Dislodgment Prevention

Relatively Increased CO2 Delivered to the Brain From the Descending Aorta Leading to an Elevated Respiratory Rate Causing Differential Hypocapnia (RIDDLER or East-West Syndrome): New Pitfalls in Awake Peripheral V-A ECMO

Indications for Extracorporeal Membrane Oxygenation in Older Adult Patients with Accidental Hypothermia and Hemodynamic Instability

Pediatric Cardiac Patients with Pulmonary Hemorrhage Supported on ECMO: An ELSO Registry Study

Prolonged ECMO Support in a Pediatric Patient with Complex Cardiac Conditions During Wartime in Kyiv, Ukraine

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