International Perfusion Association

Social:

Facebook Instagram Linkedin
IPA

Category: ECMO

Cerebral 2024

Wavelet and Time-Based Cerebral Autoregulation Analysis Using Diffuse Correlation Spectroscopy on Adults Undergoing Extracorporeal Membrane Oxygenation Therapy

This study examines cerebral autoregulation (CA) in adult patients on extracorporeal membrane oxygenation (ECMO) therapy using diffuse correlation spectroscopy (DCS), a noninvasive approach to monitoring cerebral blood flow. Neurological injuries, common in ECMO patients due to underlying conditions or the therapy itself, can impair CA, potentially worsening brain damage. Using wavelet coherence analysis (WCA), researchers found that DCS-based markers identified significant CA differences in ECMO patients with brain injuries versus those without, highlighting the potential of DCS as a monitoring tool for this population.

READ MORE
November 3, 2024
VA ECMO

A Comparative Study of Femoral Artery and Combined Femoral and Axillary Artery Cannulation in Veno-Arterial Extracorporeal Membrane Oxygenation Patients

This study investigates the clinical outcomes of two cannulation strategies—femoral artery (FA) cannulation and combined femoral and axillary artery (FA+AA) cannulation—in patients receiving veno-arterial extracorporeal membrane oxygenation (VA-ECMO) after cardiac surgery. The FA+AA group showed significant benefits in reducing chronic renal failure, platelet drop, and creatinine levels. Despite similar 30-day mortality rates, the combined approach led to fewer complications and faster recovery.

READ MORE
October 5, 2024
Hemoperfusion

Efficacy of Adjunct Hemoperfusion Compared to Standard Medical Therapy on 28-Day Mortality in Leptospirosis Patients with Renal Failure and Shock: A Single-Center Randomized Controlled Trial

This study evaluates the impact of hemoperfusion (HP) on 28-day mortality in leptospirosis patients with renal failure and septic shock. A total of 37 patients were randomized to receive either standard medical therapy (SMT) or SMT with HP. The HP group showed a 36.84% risk reduction in 28-day mortality and significant improvements in inflammatory markers, renal function, and pulmonary function. Hemoperfusion was shown to be a safe and effective adjunct therapy, promoting faster recovery and increased survival rates.

READ MORE
September 29, 2024
Thromboembolic Complications ECMO

Thromboembolic Complications in Continuous Versus Interrupted Anticoagulation During Venovenous Extracorporeal Membrane Oxygenation: A Multicenter Study

This study investigates thromboembolic complications in patients undergoing venovenous extracorporeal membrane oxygenation (ECMO) with continuous versus interrupted anticoagulation. Data from 346 patients across three ECMO centers were analyzed. Results showed no significant difference in thrombotic complications between the groups, although interruptions in anticoagulation were linked to increased thrombotic events as the frequency and duration of interruptions rose.

READ MORE
September 28, 2024
Special K

Extraction of Ketamine and Dexmedetomidine by Extracorporeal Life Support Circuits

This study investigated the extraction of ketamine and dexmedetomidine by extracorporeal life support (ECLS) circuits such as ECMO and CRRT. Using an ex-vivo system, drug concentrations were measured over time in blood-primed circuits. Results showed significant reductions in drug recovery, with ketamine recovering only 43.8% from ECMO and 3.3% from CRRT after several hours. Dexmedetomidine recovery was similarly reduced, highlighting the need for dosage adjustments during ECLS support.

READ MORE
September 26, 2024
Pediatric ECMO

Outcomes in Patients Who Received ECMO and/or Volatile Anesthetics as Rescue Therapies for Status Asthmaticus

This study explores the outcomes of pediatric patients with status asthmaticus (SA) who received either inhaled volatile anesthetics (IVA), extracorporeal membrane oxygenation (ECMO), or both as rescue therapies in a PICU setting. Among seven patients, most who received IVA were escalated to ECMO. The results suggest that early ECMO cannulation might be beneficial, though larger studies are needed to form conclusive guidelines for SA management in critically ill children.

READ MORE
September 21, 2024
ECMO Risk

Risk Factors Associated With Hospital Mortality in Non-Surgical Patients Receiving Extracorporeal Membrane Oxygenation and Continuous Renal Replacement Treatment: A Retrospective Analysis

This study identifies risk factors associated with hospital mortality in non-surgical patients receiving extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT). Using data from December 2013 to April 2023, the analysis revealed that older age, longer duration of CRRT, and CRRT implantation were independent predictors of mortality. A prediction model was developed using these factors, demonstrating good accuracy and clinical utility in estimating patient outcomes.

READ MORE
September 9, 2024
Brain ECMO

Brain Death Donors on Extracorporeal Membrane Oxygenation Support

This study examines 15 brain death donors on extracorporeal membrane oxygenation (ECMO) support, admitted to a specialized intensive care unit between 2018 and 2023. The study evaluates the effect of a strict hemodynamic monitoring schedule during a 6-hour observation period on the utilization rate of organs. Results show an increase in utilization rates from 78% to 88% with no significant differences in donor characteristics or hemodynamic data between periods. Most donors required multiple vasoactive drugs to maintain adequate perfusion.

READ MORE
September 1, 2024
ECMO Clock

Risk Factors for Mortality in Patients Receiving Extracorporeal Membrane Oxygenation

This study retrospectively analyzes the clinical data of 199 patients who received extracorporeal membrane oxygenation (ECMO) support from 2013 to 2023, revealing a mortality rate of 76.38%. The study identifies continuous renal replacement therapy (CRRT) implantation and age as independent risk factors for mortality in ECMO patients. Additionally, in those receiving combined CRRT and ECMO, the absence of congenital heart disease and a lack of surgical history are also significant mortality risk factors.

READ MORE
September 1, 2024
Load More

Post Categories