Impact of Prolonged Cardiopulmonary Bypass on Gastrointestinal Complications in Cardiac Surgery: A Retrospective Cohort Study

April 17, 2025 No Comments

This retrospective cohort study assessed the effect of prolonged cardiopulmonary bypass (CPB ≥ 120 minutes) on gastrointestinal complications (GICs) after cardiac surgery. Analyzing 1,444 patients and using propensity score matching, the study found a significantly higher rate of GICs in the prolonged CPB group. Key risk factors included hypertension, lower left ventricular ejection fraction (LVEF), and undergoing aortic surgery.

The Past, Present, and Future of Off-Pump Coronary Artery Bypass Grafting

April 16, 2025 No Comments

This review traces the evolution and prospects of off-pump coronary artery bypass grafting (OPCAB). Despite early skepticism due to technical difficulty, OPCAB offers major advantages for high-risk patients, including reduced stroke risk and faster recovery. Modern trials and meta-analyses show comparable or superior outcomes to on-pump CABG when performed by experienced surgeons. Emphasis is placed on arterial grafting, no-touch techniques, and hybrid strategies for future optimization.

Survival Analysis of Minimally Invasive Mitral Valve Surgery Versus Conventional Median Sternotomy in the United States

April 11, 2025 No Comments

This retrospective cohort study compares survival outcomes and surgical efficiency between minimally invasive mitral valve surgery (MiMVS) via mini-thoracotomy and conventional sternotomy. Among 422 elective cases, MiMVS was associated with shorter hospital stays, less postoperative bleeding, and shorter operative times. Although no significant survival difference was found, mitral valve replacement showed higher mortality risk than repair.

Vasoplegic Syndrome in Cardiac Surgery: Bridging Therapeutic Gaps with Best Practices and Future Research

April 6, 2025 No Comments

This article explores vasoplegic syndrome (VS), a serious complication following cardiac surgery involving cardiopulmonary bypass. It discusses inconsistent definitions, risk factors, and treatment strategies. Methylene blue emerges as a promising therapy due to its ability to counteract the nitric oxide-cGMP pathway. The authors advocate for standardized definitions, early intervention, and large-scale trials to validate therapeutic protocols.

Real-Time Blood Gas Management: Evaluating Quantum Perfusion System’s Accuracy Against a Standard Blood Gas Analysis in CPB

April 3, 2025 No Comments

This non-inferiority study evaluates the Quantum Perfusion System (QPS) for continuous blood gas monitoring during cardiopulmonary bypass (CPB) against the standard blood gas analyzer (BGA). Using data from 40 patients undergoing cardiac surgeries, QPS demonstrated high accuracy and agreement with BGA across all key parameters, adhering to Clinical Laboratory Improvement Amendments (CLIA) standards, and validating its utility as a trending device.

A Clinical Comparison of the Effects of Six Disposable Cardiopulmonary Bypass Circuits on Bleeding and Coagulation: A Quality Assurance Project

March 30, 2025 No Comments

This study compared six Health Canada-approved cardiopulmonary bypass (CPB) circuits in 872 cardiac surgery patients to assess their effects on bleeding and coagulation. While all circuits impaired coagulation, significant differences in bleeding severity and transfusion requirements were found after adjusting for patient and procedural factors. Circuit 6 showed the best performance in minimizing transfusion needs.

Impact of Different Sweep Gas Flow Rates on Respiratory Alkalosis and Cerebral Oxygenation During Cardiopulmonary Bypass

March 25, 2025 No Comments

This randomized clinical study assessed how varying sweep gas flow rates affect respiratory alkalosis and cerebral oxygenation during cardiopulmonary bypass (CPB) in 84 open-heart surgery patients. The findings revealed that lower sweep gas flow rates help maintain normal carbon dioxide levels and enhance cerebral oxygen saturation post-rewarming. Adjusting the sweep gas flow rate before rewarming may prevent complications associated with respiratory alkalosis.

Cardiopulmonary Bypass and Cross-Clamping Times in Aortic Valve Replacement Surgery by Ministernotomy with Sutureless Prosthesis Implantation Compared to Conventional Prosthesis: A Cross-Sectional Study

March 21, 2025 No Comments

This study compares cardiopulmonary bypass (CPB) and cross-clamping times in aortic valve replacement surgeries performed via ministernotomy using either sutureless PERCEVAL® or conventional bioprostheses. Among 93 patients, both techniques showed similar outcomes regarding CPB and cross-clamping times, hospital stays, and early postoperative complications. Echocardiographic results improved postoperatively in both groups.

Sex-Related Differences in Systemic Inflammatory Response and Outcomes After Cardiac Surgery and Cardiopulmonary Bypass

March 17, 2025 No Comments

This study investigates the impact of sex on systemic inflammatory response syndrome (SIRS) and outcomes after cardiac surgery. Analyzing 1,005 patients, researchers found that women had a higher incidence of SIRS (41.8% vs. 22.8%) and worse outcomes, including prolonged ICU stays and increased need for vasopressor support. SIRS mediated over 50% of the sex-related risks, with preoperative anemia and hyperlactatemia as contributing factors. Addressing inflammation may improve outcomes for female patients.

Buckberg vs. Del Nido in Isolated Aortic Valve Replacement: A Prospective, Two-Center, Randomized Trial

March 16, 2025 No Comments

This study compares Buckberg (BS) and Del Nido (DNS) cardioplegia in isolated aortic valve replacement (AVR) through a two-center randomized trial with 311 patients. While postoperative creatine kinase and troponin levels showed no significant differences, the DNS group had better intraoperative glycemic control, higher spontaneous rhythm rates, and fewer cases of ventricular fibrillation requiring defibrillation. The study supports DNS as a viable alternative with workflow advantages.

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Impact of Prolonged Cardiopulmonary Bypass on Gastrointestinal Complications in Cardiac Surgery: A Retrospective Cohort Study

The Past, Present, and Future of Off-Pump Coronary Artery Bypass Grafting

Survival Analysis of Minimally Invasive Mitral Valve Surgery Versus Conventional Median Sternotomy in the United States

Vasoplegic Syndrome in Cardiac Surgery: Bridging Therapeutic Gaps with Best Practices and Future Research

Real-Time Blood Gas Management: Evaluating Quantum Perfusion System’s Accuracy Against a Standard Blood Gas Analysis in CPB

A Clinical Comparison of the Effects of Six Disposable Cardiopulmonary Bypass Circuits on Bleeding and Coagulation: A Quality Assurance Project

Impact of Different Sweep Gas Flow Rates on Respiratory Alkalosis and Cerebral Oxygenation During Cardiopulmonary Bypass

Cardiopulmonary Bypass and Cross-Clamping Times in Aortic Valve Replacement Surgery by Ministernotomy with Sutureless Prosthesis Implantation Compared to Conventional Prosthesis: A Cross-Sectional Study

Sex-Related Differences in Systemic Inflammatory Response and Outcomes After Cardiac Surgery and Cardiopulmonary Bypass

Buckberg vs. Del Nido in Isolated Aortic Valve Replacement: A Prospective, Two-Center, Randomized Trial

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