Hemolysis and Kidney Injury Risk After Cardiac Surgery

Hemolysis and Acute Kidney Injury Following Cardiac Surgery With Cardiopulmonary Bypass in Patients With Preexisting Renal Dysfunction

March 23, 2026 No Comments

This study examines whether hemolysis, measured by cell-free hemoglobin (CFHb), predicts acute kidney injury (AKI) after cardiac surgery in patients with preexisting renal dysfunction. Among 89 patients, 21% developed AKI. Although hemolysis and endothelial damage increased postoperatively, CFHb did not independently predict AKI or improve predictive models, suggesting limited clinical utility as a biomarker.

Viscoelastic Monitoring Guiding Hemostasis During Cardiac Surgery

A Prospective Analysis of Viscoelastic Assays, Platelet Aggregometry, and Standard Laboratory Tests in Predicting Perioperative Blood Loss in Cardiac Surgery

March 14, 2026 No Comments

This prospective observational study of 79 cardiac surgery patients evaluated whether viscoelastic testing (ROTEM), platelet aggregometry, or standard coagulation tests best predict perioperative bleeding. Clot firmness measured by FIBTEM A10 strongly correlated with blood loss using the Hb/kg Index, while platelet count, platelet aggregation, and conventional tests did not. A FIBTEM A10 cutoff of 12 mm accurately detected hypofibrinogenemia, supporting fibrinogen-focused transfusion strategies.

The Impact of Intraoperative Fibrinogen Replacement Therapy on the Clinical Outcome of Surgical Therapy for Type A Acute Aortic Dissection

March 6, 2026 No Comments

This retrospective study evaluated the role of fibrinogen replacement therapy (FRT) using fibrinogen concentrate during emergency surgery for acute type A aortic dissection (ATAAD). Among 87 patients, FRT significantly improved postoperative fibrinogen levels and helped maintain hemostasis without increasing complications. Although intraoperative blood loss was higher in the FRT group due to more severe coagulopathy, postoperative bleeding was similar between groups, suggesting FRT effectively stabilizes coagulation during complex aortic surgery.

A Prospective Observational Study on Role of Intraoperative Renal & Muscle Oxygen Saturation on Post-Operative Serum Creatinine Level in Patients Undergoing Cardiac Surgery on Cardiopulmonary Bypass

March 5, 2026 No Comments

This prospective observational study evaluated whether intraoperative renal (SrO₂) and thenar muscle oxygen saturation (SmO₂), measured using near-infrared spectroscopy (NIRS), could predict post-operative increases in serum creatinine in patients undergoing cardiac surgery with cardiopulmonary bypass. Among 55 patients, a >20% decrease in renal oxygen saturation strongly predicted post-operative creatinine rise, while a 15% decrease in muscle oxygen saturation also showed strong predictive value. Both parameters were significantly correlated.

Preoperative Anemia Management and Its Economic Impact on Red Blood Cell Transfusion in Cardiac Surgery

Predictors and Economic Impact of Red Blood Cell Transfusion in Cardiac Surgery: A Simulated Cost Reduction Model for Preoperative Anemia Management

February 16, 2026 No Comments

This retrospective cohort study of 661 elective cardiac surgery patients identified preoperative anemia as the strongest independent predictor of red blood cell (RBC) transfusion (OR 3.67). Transfusion was associated with longer hospital stay, higher infection rates, prolonged ventilation, and a median cost increase of €2264 per patient. A simulation model estimated that eliminating preoperative anemia could prevent 47 transfusions and save €106 429 over 13 months.

Why Certification Matters: Elevate Your Career in ECMO & Blood Management

September 25, 2025 No Comments

Certification in extracorporeal life support and blood management is more than a credential—it’s a statement of expertise, trust, and commitment to excellence. AmSECT/IBBM certification sets you apart in a competitive field, opening career opportunities, building credibility, and ensuring lifelong learning. Stay ahead with industry advancements, expand your professional network, and gain recognition for your skills. Spring applications close April 25, 2025

Evaluation of Intraoperative and Postoperative Blood Cell Salvage Use in Cardiac Surgery with Cardiopulmonary Bypass

June 3, 2025 No Comments

This study investigates the impact of using blood cell salvage (BCS) during and after cardiac surgery with cardiopulmonary bypass (CPB). Among 41 patients, those using BCS showed significantly improved hemoglobin and hematocrit levels, fewer red blood cell transfusions, lower infection rates, and shorter hospital stays. The findings support integrating BCS into Patient Blood Management strategies for better clinical outcomes.

Comparative Efficacy of Blood Salvage Techniques After Cardiopulmonary Bypass: Centrifugation, Modified Ultrafiltration, and Hemobag Systems in Adult Cardiac Surgery

May 20, 2025 No Comments

Four studies explore blood conservation strategies following cardiopulmonary bypass (CPB) in adult cardiac surgery. Techniques like centrifugation (CF), modified ultrafiltration (MUF), and Hemobag (HB) processing vary in their effectiveness. MUF and HB methods consistently reduce postoperative transfusions and improve hematologic markers compared to CF, supporting their broader use in adult cardiac surgical care.

Evaluation of Transcutaneous Non-Invasive Blood Gas Analysis for Monitoring Gas Exchange in Pediatric Cardiac Surgical Patients Post Extubation

April 13, 2025 No Comments

This study evaluates the effectiveness of transcutaneous blood gas monitoring (TcPCO₂ and TcPO₂) in detecting carbon dioxide and oxygen levels in pediatric cardiac surgery patients after extubation. It found a strong correlation between TcPCO₂ and arterial PaCO₂, suggesting transcutaneous CO₂ can be a reliable, non-invasive monitoring tool. However, TcPO₂ showed less precision and cannot substitute PaO₂.

Vasoplegic Syndrome in Cardiac Surgery: Bridging Therapeutic Gaps with Best Practices and Future Research

April 6, 2025 No Comments

This article explores vasoplegic syndrome (VS), a serious complication following cardiac surgery involving cardiopulmonary bypass. It discusses inconsistent definitions, risk factors, and treatment strategies. Methylene blue emerges as a promising therapy due to its ability to counteract the nitric oxide-cGMP pathway. The authors advocate for standardized definitions, early intervention, and large-scale trials to validate therapeutic protocols.