Explore articles, research, and perspectives from the International Perfusion Association.
A randomized trial compared Custodiol, del Nido, and modified del Nido in 99 adults. Review troponin, transfusion, electrolyte findings, and evidence limits.
A five-patient case series explores infrared thermography for detecting epicardial and cardioplegia-line cooling during CPB in cold agglutinin disease.
A 60-child randomized trial tests dexmedetomidine in modified del Nido cardioplegia, with promising recovery findings but important dosing and reporting inconsistencies.
A focused review examines cardioplegia in aortic stenosis, including ventricular hypertrophy, solution choice, temperature, delivery, dosing, and redosing.
A prospective study of 94 CABG patients linked coronary sinus lactate above 3 mmol/L five minutes after reperfusion with more treated postoperative atrial fibrillation.
A Colombian study of 179 adults undergoing isolated aortic valve replacement found lower modeled costs with Del Nido than Custodiol cardioplegia. Thirty-day survival was
A 103-patient retrospective Bentall study associated hybrid cardioplegia with less drainage and fewer bleeding re-explorations, without significant transfusion or mortality differences.
A randomized trial of 58 adults compared lactated Ringer’s–based modified del Nido with Custodiol cardioplegia. Modified del Nido produced lower 24-hour troponin I, faster
In a randomized trial of 60 adults undergoing CABG for left main coronary artery disease, combined antegrade–retrograde blood cardioplegia did not significantly reduce peak
This systematic review and Bayesian meta-analysis evaluated whether adding propofol to cardioplegic solution improves myocardial protection during cardiac surgery. Five randomized controlled trials involving
This experimental rat-heart study tested whether ranolazine protects the myocardium through pathways similar to ischemic preconditioning. Using a Langendorff ischemia-reperfusion model, ranolazine reduced infarct
This retrospective single-center study compared four cardioplegia strategies in 543 patients undergoing minimally invasive aortic valve replacement from 2010 to 2025. After inverse probability
