Cardiopulmonary Bypass in a Pediatric Patient with Factor XII Deficiency

September 21, 2024 No Comments

This case report discusses the challenges of managing cardiopulmonary bypass (CPB) in an 8-month-old pediatric patient with factor XII deficiency, a rare coagulopathy that complicates anticoagulation monitoring. The use of the Hemochron Signature Elite with ACT+ cartridges provided reliable anticoagulation monitoring during surgery. The report reviews current strategies for managing CPB in patients with this condition, highlighting the importance of specialized tools for predictable results.

Top 5 Reasons to Obtain an IBBM Certification in Blood Management and ECMO

August 24, 2024 No Comments

In the competitive healthcare industry, certification in blood management or ECMO through the AmSECT International Board of Blood Management (IBBM) can significantly elevate your career. Certification demonstrates leadership, earns respect from peers, sharpens your skills, enhances career opportunities, and boosts earning potential. Specialized certifications such as PBMT, PBMS, CES-A, and CES-P mark you as a committed expert in patient care.

Acute Normovolemic Hemodilution in Cardiac Surgery: Rationale and Design of a Multicenter Randomized Trial

August 9, 2024 No Comments

This study explores whether Acute Normovolemic Hemodilution (ANH) can reduce the need for Red Blood Cell (RBC) transfusions after cardiac surgery. The multicenter, randomized controlled trial involves patients scheduled for elective cardiac surgery with cardiopulmonary bypass. Participants are assigned to receive either ANH or standard treatment. The primary outcome is the rate of RBC transfusion, with secondary outcomes including mortality and complications.

Methodologic Quality and Pharmacotherapy Recommendations for Patient Blood Management Guidelines for Cardiac Surgery on Cardiopulmonary Bypass

June 29, 2024 No Comments

This study evaluated the methodology and pharmacotherapy recommendations of Patient Blood Management (PBM) guidelines for cardiac surgery under cardiopulmonary bypass (CPB). It analyzed nine guidelines using the AGREE II tool, finding that “Stakeholder involvement” scored lowest. Drug therapy strategies include anemia therapy, antithrombotic and anticoagulation drugs, and hemostatic drugs, with distinct recommendations for pediatric and adult patients.

Can a Low Prime Volume Arterial Filter Be Used as an Alternative for a Venous Bubble Trap in Minimal Extracorporeal Circulation? An In Vitro Investigation

May 22, 2024 No Comments

This study examines whether an arterial filter with a small prime volume can effectively replace a venous bubble trap (VBT) in a minimal extracorporeal circulation (MiECC) system used during cardiac surgery. The study compared air removal capabilities of an arterial filter and three VBTs: VBT160, VBT8, and VARD. Results showed the AF100 arterial filter demonstrated similar, and in some cases better, performance in removing air and gaseous microemboli (GME) compared to VBTs. However, the placement of the arterial filter in the venous line is considered off-label use.

Use of Thromboelastography in Coronary Artery Bypass Grafting in a Patient With Factor Ⅴ Deficiency With Platelet Function Disorders: A Case Report and Literature Review

May 15, 2024 No Comments

This case report examines the role of thromboelastography (TEG) in managing a 64-year-old hemodialysis patient with Factor V deficiency and platelet function disorders undergoing coronary artery bypass grafting. Despite a mild decrease in Factor V activity, preoperative transfusions corrected platelet dysfunction, allowing for successful surgery. Postoperative strategies were also TEG-guided, showcasing its utility in complex clinical scenarios.

Activated Clotting Time Value as an Independent Predictor of Postoperative Bleeding and Transfusion

May 8, 2024 No Comments

This study examines the incidence and predictors of bleeding and thrombosis in patients treated with extracorporeal cardiopulmonary resuscitation (ECPR) after out-of-hospital cardiac arrest due to ventricular tachycardia/fibrillation. Among 200 patients, 67.5% experienced major bleeding, primarily from CPR-related trauma. Decreased fibrinogen levels were linked to bleeding, but bleeding did not significantly affect in-hospital mortality. Thrombosis occurred in 23.5% of patients and was not associated with in-hospital death.

Bleeding and Thrombosis in Patients With Out-of-Hospital Ventricular Tachycardia/Ventricular Fibrillation Arrest Treated With Extracorporeal Cardiopulmonary Resuscitation

May 8, 2024 No Comments

Intraoperative Haemoadsorption for Antithrombotic Drug Removal During Cardiac Surgery: Initial Report of the International Safe and Timely Antithrombotic Removal (STAR) Registry

May 8, 2024 No Comments

The STAR registry study explores the use of haemoadsorption for removing antithrombotic drugs during cardiac surgery to reduce bleeding risks. This report covers 165 patients from Austria, Germany, Sweden, and the UK. Patients on P2Y12 inhibitors and DOACs were assessed. The device, integrated into the cardiopulmonary bypass, showed promising results in mitigating bleeding risks. Group 1 (P2Y12) and Group 2 (DOAC) patients experienced similar bleeding events, suggesting the procedure’s safety and effectiveness.

Effect of Geography on the Use of Ultrafiltration During Cardiac Surgery with Cardiopulmonary Bypass

April 22, 2024 No Comments

This study explores geographic differences in ultrafiltration (UF) use during cardiopulmonary bypass in the US, analyzing data from 92,859 cardiac surgeries across four regions. Results reveal significant regional disparities in UF usage and volumes, with the Northeast and West employing UF more frequently than the Midwest and South. Variations were also noted in intraoperative urine output and red blood cell transfusion rates, prompting calls for further research into the causes of these differences.

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Cardiopulmonary Bypass in a Pediatric Patient with Factor XII Deficiency

Top 5 Reasons to Obtain an IBBM Certification in Blood Management and ECMO

Acute Normovolemic Hemodilution in Cardiac Surgery: Rationale and Design of a Multicenter Randomized Trial

Methodologic Quality and Pharmacotherapy Recommendations for Patient Blood Management Guidelines for Cardiac Surgery on Cardiopulmonary Bypass

Can a Low Prime Volume Arterial Filter Be Used as an Alternative for a Venous Bubble Trap in Minimal Extracorporeal Circulation? An In Vitro Investigation

Use of Thromboelastography in Coronary Artery Bypass Grafting in a Patient With Factor Ⅴ Deficiency With Platelet Function Disorders: A Case Report and Literature Review

Activated Clotting Time Value as an Independent Predictor of Postoperative Bleeding and Transfusion

Bleeding and Thrombosis in Patients With Out-of-Hospital Ventricular Tachycardia/Ventricular Fibrillation Arrest Treated With Extracorporeal Cardiopulmonary Resuscitation

Intraoperative Haemoadsorption for Antithrombotic Drug Removal During Cardiac Surgery: Initial Report of the International Safe and Timely Antithrombotic Removal (STAR) Registry

Effect of Geography on the Use of Ultrafiltration During Cardiac Surgery with Cardiopulmonary Bypass

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