Evaluation of Intraoperative and Postoperative Blood Cell Salvage Use in Cardiac Surgery with Cardiopulmonary Bypass

This study investigates the impact of using blood cell salvage (BCS) during and after cardiac surgery with cardiopulmonary bypass (CPB). Among 41 patients, those using BCS showed significantly improved hemoglobin and hematocrit levels, fewer red blood cell transfusions, lower infection rates, and shorter hospital stays. The findings support integrating BCS into Patient Blood Management strategies for better clinical outcomes.

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Comparative Efficacy of Blood Salvage Techniques After Cardiopulmonary Bypass: Centrifugation, Modified Ultrafiltration, and Hemobag Systems in Adult Cardiac Surgery

Four studies explore blood conservation strategies following cardiopulmonary bypass (CPB) in adult cardiac surgery. Techniques like centrifugation (CF), modified ultrafiltration (MUF), and Hemobag (HB) processing vary in their effectiveness. MUF and HB methods consistently reduce postoperative transfusions and improve hematologic markers compared to CF, supporting their broader use in adult cardiac surgical care.

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Evaluation of Transcutaneous Non-Invasive Blood Gas Analysis

Evaluation of Transcutaneous Non-Invasive Blood Gas Analysis for Monitoring Gas Exchange in Pediatric Cardiac Surgical Patients Post Extubation

This study evaluates the effectiveness of transcutaneous blood gas monitoring (TcPCO₂ and TcPO₂) in detecting carbon dioxide and oxygen levels in pediatric cardiac surgery patients after extubation. It found a strong correlation between TcPCO₂ and arterial PaCO₂, suggesting transcutaneous CO₂ can be a reliable, non-invasive monitoring tool. However, TcPO₂ showed less precision and cannot substitute PaO₂.

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Vasoplegic Syndrome in Cardiac Surgery

Vasoplegic Syndrome in Cardiac Surgery: Bridging Therapeutic Gaps with Best Practices and Future Research

This article explores vasoplegic syndrome (VS), a serious complication following cardiac surgery involving cardiopulmonary bypass. It discusses inconsistent definitions, risk factors, and treatment strategies. Methylene blue emerges as a promising therapy due to its ability to counteract the nitric oxide-cGMP pathway. The authors advocate for standardized definitions, early intervention, and large-scale trials to validate therapeutic protocols.

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Perioperative Bleeding Is Not an Independent Risk Factor for Acute Kidney Injury

Perioperative Bleeding Is Not an Independent Risk Factor for Acute Kidney Injury in On-pump Cardiac Surgery—A Post-hoc Analysis of a Randomized Clinical Trial

A post-hoc analysis of the ALBICS randomized trial with 1,386 cardiac surgery patients found that perioperative bleeding, as classified by the Universal Definition of Perioperative Bleeding (UDPB), was not independently linked to acute kidney injury (AKI). Rather, bleeding indirectly contributed to AKI through hypotension and fluid overload. The only transfusion product independently associated with AKI was fresh frozen plasma.

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CytoSorb Hemoadsorption of Apixaban

CytoSorb Hemoadsorption of Apixaban During Cardio-Pulmonary Bypass for Heart Transplantation

This case study reports on the successful intraoperative removal of apixaban using a CytoSorb hemoadsorption device during emergency heart transplantation. The 61-year-old patient, previously on apixaban, underwent cardiopulmonary bypass (CPB), during which the device significantly reduced anticoagulant levels without complications. The results suggest CytoSorb may offer a viable method to manage DOACs in urgent cardiac surgery settings.

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Indications for Extracorporeal Membrane Oxygenation in Older Adult Patients with Accidental Hypothermia and Hemodynamic Instability

Indications for Extracorporeal Membrane Oxygenation in Older Adult Patients with Accidental Hypothermia and Hemodynamic Instability

This study analyzes the efficacy of extracorporeal membrane oxygenation (ECMO) in older adults with accidental hypothermia (AH) and hemodynamic instability before cardiac arrest. A post-hoc analysis of the ICE-CRASH study (2019–2022) found no significant survival difference between ECMO and non-ECMO patients at 28 days. ECMO accelerated rewarming but increased bleeding complications. The study concludes ECMO may not benefit this patient group, challenging existing treatment criteria.

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Why Certification Matters: Elevate Your Career in ECMO & Blood Management

Certification in extracorporeal life support and blood management is more than a credential—it’s a statement of expertise, trust, and commitment to excellence. AmSECT/IBBM certification sets you apart in a competitive field, opening career opportunities, building credibility, and ensuring lifelong learning. Stay ahead with industry advancements, expand your professional network, and gain recognition for your skills. Spring applications close April 25, 2025

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Does Intraoperative Cell-Salvaged Autologous Blood Transfusion in Metastatic Spine Tumour Surgery Impact Clinical Outcomes? A Prospective Clinical Study With 4-Year Follow-Up

Does Intraoperative Cell-Salvaged Autologous Blood Transfusion in Metastatic Spine Tumour Surgery Impact Clinical Outcomes? A Prospective Clinical Study With 4-Year Follow-Up

This prospective clinical study evaluates the impact of intraoperative cell-salvaged blood transfusion (SBT) on long-term clinical outcomes in metastatic spine tumour surgery (MSTS). Comparing SBT with allogeneic blood transfusion (ABT) and no transfusion (NBT), the study finds no significant difference in overall survival or tumour progression over four years. The findings support SBT as a viable alternative to ABT, reducing risks and dependency on donor blood.

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Effect of Intraoperative Fluid Volume on Postoperative Pulmonary Complications in Thoracic Surgeries: A Systematic Review and Meta-Analysis

Effect of Intraoperative Fluid Volume on Postoperative Pulmonary Complications in Thoracic Surgeries: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis investigates the impact of intraoperative fluid volume on postoperative pulmonary complications (PPCs) in thoracic surgeries. Analyzing 11 studies, the review finds that higher intraoperative fluid infusion is associated with an increased risk of PPCs. A restrictive fluid strategy may be safer, though high heterogeneity and potential biases necessitate further randomized controlled trials to establish definitive recommendations.

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