Perioperative Bleeding Is Not an Independent Risk Factor for Acute Kidney Injury in On-pump Cardiac Surgery—A Post-hoc Analysis of a Randomized Clinical Trial

April 1, 2025 No Comments

A post-hoc analysis of the ALBICS randomized trial with 1,386 cardiac surgery patients found that perioperative bleeding, as classified by the Universal Definition of Perioperative Bleeding (UDPB), was not independently linked to acute kidney injury (AKI). Rather, bleeding indirectly contributed to AKI through hypotension and fluid overload. The only transfusion product independently associated with AKI was fresh frozen plasma.

CytoSorb Hemoadsorption of Apixaban During Cardio-Pulmonary Bypass for Heart Transplantation

March 29, 2025 No Comments

This case study reports on the successful intraoperative removal of apixaban using a CytoSorb hemoadsorption device during emergency heart transplantation. The 61-year-old patient, previously on apixaban, underwent cardiopulmonary bypass (CPB), during which the device significantly reduced anticoagulant levels without complications. The results suggest CytoSorb may offer a viable method to manage DOACs in urgent cardiac surgery settings.

Indications for Extracorporeal Membrane Oxygenation in Older Adult Patients with Accidental Hypothermia and Hemodynamic Instability

March 16, 2025 No Comments

This study analyzes the efficacy of extracorporeal membrane oxygenation (ECMO) in older adults with accidental hypothermia (AH) and hemodynamic instability before cardiac arrest. A post-hoc analysis of the ICE-CRASH study (2019–2022) found no significant survival difference between ECMO and non-ECMO patients at 28 days. ECMO accelerated rewarming but increased bleeding complications. The study concludes ECMO may not benefit this patient group, challenging existing treatment criteria.

Why Certification Matters: Elevate Your Career in ECMO & Blood Management

March 12, 2025 No Comments

Certification in extracorporeal life support and blood management is more than a credential—it’s a statement of expertise, trust, and commitment to excellence. AmSECT/IBBM certification sets you apart in a competitive field, opening career opportunities, building credibility, and ensuring lifelong learning. Stay ahead with industry advancements, expand your professional network, and gain recognition for your skills. Spring applications close April 25, 2025

Does Intraoperative Cell-Salvaged Autologous Blood Transfusion in Metastatic Spine Tumour Surgery Impact Clinical Outcomes? A Prospective Clinical Study With 4-Year Follow-Up

March 10, 2025 No Comments

This prospective clinical study evaluates the impact of intraoperative cell-salvaged blood transfusion (SBT) on long-term clinical outcomes in metastatic spine tumour surgery (MSTS). Comparing SBT with allogeneic blood transfusion (ABT) and no transfusion (NBT), the study finds no significant difference in overall survival or tumour progression over four years. The findings support SBT as a viable alternative to ABT, reducing risks and dependency on donor blood.

Effect of Intraoperative Fluid Volume on Postoperative Pulmonary Complications in Thoracic Surgeries: A Systematic Review and Meta-Analysis

March 9, 2025 No Comments

This systematic review and meta-analysis investigates the impact of intraoperative fluid volume on postoperative pulmonary complications (PPCs) in thoracic surgeries. Analyzing 11 studies, the review finds that higher intraoperative fluid infusion is associated with an increased risk of PPCs. A restrictive fluid strategy may be safer, though high heterogeneity and potential biases necessitate further randomized controlled trials to establish definitive recommendations.

The Role of Continuous Monitoring of Venous Drainage Flow and Integrated Oxygen Extraction (ERiO2) via Bilateral Near-Infrared Spectroscopy in Cerebral Perfusion During Aortic Arch Surgery

March 6, 2025 No Comments

This study evaluates the role of continuous monitoring of venous drainage flow and oxygen extraction (ERiO2) using near-infrared spectroscopy (NIRS) in cerebral perfusion during aortic arch surgery. A retrospective review of 10 patients undergoing selective antegrade cerebral perfusion (SACP) found a strong correlation (r = 0.91, p < 0.01) between ERiO2 and NIRS-derived regional oxygen saturation (rSO2). The study suggests that integrated monitoring improves perfusion management and neurological outcomes.

Outcomes and Biochemical Parameters Following Cardiac Surgery: Effects of Transfusion of Residual Blood Using Centrifugation and Multiple-Pass Hemoconcentration

March 4, 2025 No Comments

This study compares centrifugation (CF) and multiple-pass hemoconcentration (MPH) for salvaging residual blood after cardiopulmonary bypass. A randomized trial with 61 patients found that MPH resulted in higher postoperative albumin, total protein, fibrinogen, and platelet levels compared to CF. While CF processed blood faster and cleared heparin more consistently, MPH was associated with lower allogeneic transfusion needs and reduced fluid retention. Overall, MPH demonstrated improved biochemical and clinical outcomes.

Transfusion Use and Hemoglobin Levels by Blood Conservation Method After Cardiopulmonary Bypass

March 4, 2025 No Comments

This study evaluates three blood conservation techniques—online modified ultrafiltration (MUF), off-line MUF, and centrifugation—following cardiopulmonary bypass. A cohort of 99 patients was analyzed for transfusion rates, hemoglobin levels, and fluid balance. Results indicated no significant advantage of online MUF in reducing transfusions. Off-line MUF had the lowest transfusion rates, while online MUF showed greater hemoglobin improvement, likely due to fluid shifts.

Risk Factors Influencing the Prognosis of Patients with Acute Myocardial Infarction and Cardiogenic Shock Undergoing Extracorporeal Membrane Oxygenation Therapy

February 22, 2025 No Comments

This study examines risk factors affecting survival in patients with acute myocardial infarction (AMI) and cardiogenic shock (CS) treated with extracorporeal membrane oxygenation (ECMO). Analyzing 63 cases from 2020–2023, findings indicate that elevated arterial blood lactate, prolonged time to PCI, and higher vasoactive-inotropic scores (VIS) are key predictors of poor prognosis. Early intervention, including timely PCI and metabolic stabilization, is crucial to improving survival outcomes.

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Perioperative Bleeding Is Not an Independent Risk Factor for Acute Kidney Injury in On-pump Cardiac Surgery—A Post-hoc Analysis of a Randomized Clinical Trial

CytoSorb Hemoadsorption of Apixaban During Cardio-Pulmonary Bypass for Heart Transplantation

Indications for Extracorporeal Membrane Oxygenation in Older Adult Patients with Accidental Hypothermia and Hemodynamic Instability

Why Certification Matters: Elevate Your Career in ECMO & Blood Management

Does Intraoperative Cell-Salvaged Autologous Blood Transfusion in Metastatic Spine Tumour Surgery Impact Clinical Outcomes? A Prospective Clinical Study With 4-Year Follow-Up

Effect of Intraoperative Fluid Volume on Postoperative Pulmonary Complications in Thoracic Surgeries: A Systematic Review and Meta-Analysis

The Role of Continuous Monitoring of Venous Drainage Flow and Integrated Oxygen Extraction (ERiO2) via Bilateral Near-Infrared Spectroscopy in Cerebral Perfusion During Aortic Arch Surgery

Outcomes and Biochemical Parameters Following Cardiac Surgery: Effects of Transfusion of Residual Blood Using Centrifugation and Multiple-Pass Hemoconcentration

Transfusion Use and Hemoglobin Levels by Blood Conservation Method After Cardiopulmonary Bypass

Risk Factors Influencing the Prognosis of Patients with Acute Myocardial Infarction and Cardiogenic Shock Undergoing Extracorporeal Membrane Oxygenation Therapy

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