
Comparison of 6% Hydroxyethyl Starch 130/0.4 vs 5% Albumin in Cardiopulmonary Bypass for Cardiac Surgery
This meta-analysis of 12 studies (908 patients) compares 6% hydroxyethyl starch (HES 130/0.4) and 5% albumin in cardiac surgery with cardiopulmonary bypass. Results show no significant differences in blood loss, transfusion needs, ICU stay, or mortality. However, HES is associated with a significantly higher risk of acute kidney injury, raising concerns about its renal safety despite similar overall efficacy.
