Zero-Balance Ultrafiltration Reduces Postoperative Delirium After Cardiac Surgery with Cardiopulmonary Bypass: A Randomized Controlled Trial

February 5, 2026 No Comments

This single-center randomized controlled trial evaluated whether adding zero-balance ultrafiltration (Z-BUF) to conventional ultrafiltration during cardiopulmonary bypass reduces postoperative delirium after cardiac surgery. Among 106 analyzed patients, Z-BUF significantly lowered delirium incidence within 7 postoperative days compared with conventional ultrafiltration alone, while no significant differences were observed in longer-term cognitive outcomes at 1 or 3 months.

Selective Ex Vivo Lung Perfusion in Donation After Circulatory Death Transplantation

Ex Vivo Lung Perfusion in Donation After Circulatory Death Lung Transplantation: A Systematic Review and Meta-Analysis

February 5, 2026 No Comments

This systematic review and meta-analysis evaluated whether ex vivo lung perfusion (EVLP) improves outcomes in donation after circulatory death (DCD) lung transplantation. Across five observational studies including 654 patients, EVLP showed no significant differences in grade 3 primary graft dysfunction, ICU or hospital length of stay, short-term survival, pneumonia, or acute rejection compared with direct transplantation. Findings support selective rather than routine EVLP use.