International Perfusion Association

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IPA

Day: March 4, 2025

Lethal Myocardial Infarction in a Neonate During Extracorporeal Membrane Oxygenation

Lethal Myocardial Infarction in a Neonate During Extracorporeal Membrane Oxygenation

This case study explores a neonate with congenital diaphragmatic hernia (CDH) who experienced a lethal myocardial infarction (MI) while on extracorporeal membrane oxygenation (ECMO). The patient developed a large thrombus extending from the arterial cannula into the left main coronary artery, leading to severe cardiac dysfunction. Despite anticoagulation efforts, the clot progressed, resulting in a fatal outcome. The study highlights the challenges of managing neonatal ECMO and intracardiac thrombosis.

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March 4, 2025
Outcomes and Biochemical Parameters Following Cardiac Surgery: Effects of Transfusion of Residual Blood Using Centrifugation and Multiple-Pass Hemoconcentration

Outcomes and Biochemical Parameters Following Cardiac Surgery: Effects of Transfusion of Residual Blood Using Centrifugation and Multiple-Pass Hemoconcentration

This study compares centrifugation (CF) and multiple-pass hemoconcentration (MPH) for salvaging residual blood after cardiopulmonary bypass. A randomized trial with 61 patients found that MPH resulted in higher postoperative albumin, total protein, fibrinogen, and platelet levels compared to CF. While CF processed blood faster and cleared heparin more consistently, MPH was associated with lower allogeneic transfusion needs and reduced fluid retention. Overall, MPH demonstrated improved biochemical and clinical outcomes.

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March 4, 2025
Transfusion Use and Hemoglobin Levels by Blood Conservation Method After Cardiopulmonary Bypass

Transfusion Use and Hemoglobin Levels by Blood Conservation Method After Cardiopulmonary Bypass

This study evaluates three blood conservation techniques—online modified ultrafiltration (MUF), off-line MUF, and centrifugation—following cardiopulmonary bypass. A cohort of 99 patients was analyzed for transfusion rates, hemoglobin levels, and fluid balance. Results indicated no significant advantage of online MUF in reducing transfusions. Off-line MUF had the lowest transfusion rates, while online MUF showed greater hemoglobin improvement, likely due to fluid shifts.

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March 4, 2025

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