International Perfusion Association

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IPA

Day: April 21, 2024

Mad Kidney

Risk Prediction Models for Renal Function Decline After Cardiac Surgery Within Different Preoperative Glomerular Filtration Rate Strata

This study focuses on developing risk prediction models to identify patients at risk of renal function decline post-cardiac surgery. Using data from 24,904 patients at Fuwai Hospital, the study found significant variances in renal decline risks across different preoperative glomerular filtration rate (eGFR) strata. Notably, patients with higher eGFR levels pre-surgery showed increased risk. The research produced distinct nomograms for each eGFR category, demonstrating good predictive accuracy and providing a practical tool for postoperative renal monitoring.

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April 21, 2024
Blood Hero

Methodologic Quality and Pharmacotherapy Recommendations for Patient Blood Management Guidelines for Cardiac Surgery on Cardiopulmonary Bypass

This study evaluates the methodological quality and pharmacotherapy recommendations of Patient Blood Management (PBM) guidelines for cardiac surgery involving cardiopulmonary bypass (CPB). Analyzing guidelines using the AGREE II tool, it highlights varying consistency across documents, especially in stakeholder involvement. The study reviews drug therapy strategies including anemia therapy, perioperative antithrombotic administration, intraoperative anticoagulation, and hemostatic drug use, noting a lack of pediatric-specific evidence and the cautious use of certain drugs post-surgery.

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April 21, 2024
Brain Hemmorage

Impact of Postoperative Cerebral Complications in Acute Infective Endocarditis: A Retrospective Single-Center Study

This retrospective study at a single center explored the impact of preoperative cerebral complications on patients with acute infective endocarditis (IE). Among 31 patients analyzed, those with intracranial findings prior to surgery did not experience a worse postoperative course despite being older and having more complex clinical profiles. Notably, one patient without previous cerebral issues developed a cerebral hemorrhage postoperatively, highlighting the need for careful monitoring and preventative strategies for all IE patients, regardless of initial cerebral status.

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April 21, 2024
COVID Education

Durability of Original Monovalent mRNA Vaccine Effectiveness Against COVID-19 Omicron-Associated Hospitalization in Children and Adolescents – United States, 2021-2023

This study assesses the durability of the original monovalent mRNA COVID-19 vaccine in preventing hospitalization due to the Omicron variant among U.S. children aged 5-18. Between December 2021 and October 2023, vaccine effectiveness (VE) was 52% within 120 days of the last dose but dropped to 19% for doses received 120-364 days prior. VE was 31% when the last dose was within the past year. For severe cases requiring intensive interventions, VE was higher shortly after vaccination but decreased over time. The study supports CDC recommendations for updated vaccinations in children and adolescents.

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April 21, 2024
Del Nido Cardio

Comparison of Del Nido Cardioplegia and Crystalloid Blood Cardioplegia on Arrhythmia and Early Results

This study compares the efficacy of Del Nido cardioplegia (DN) and traditional crystalloid blood cardioplegia in patients undergoing coronary artery bypass surgery, focusing on their effects on arrhythmias and early surgical outcomes. The research involved 175 patients using crystalloid cardioplegia and 150 patients using DN solution. Findings suggest that DN solution, particularly when part of the dose is administered through grafts, leads to better control of arrhythmias post-surgery, reduced need for pacing, and shorter hospital and intensive care unit stays.

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April 21, 2024

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