International Perfusion Association

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Day: March 26, 2024

ECMO West

Impact of ECMO-Related Complications on In-Hospital Mortality: A Single-Center Retrospective Study

This study examines the association between complications arising from Extracorporeal Membrane Oxygenation (ECMO) treatment and in-hospital mortality among adult patients. It involves a retrospective analysis of 856 ECMO interventions, revealing that vascular and cerebrovascular complications occurred in 20.2% and 13.6% of cases, respectively. The overall in-hospital mortality rate was 48.7%. Surprisingly, the analysis found no significant correlation between ECMO-related complications and an increased risk of in-hospital death, suggesting that while ECMO complications are prevalent, they do not independently contribute to patient mortality.

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ECMO China

Intra-Aortic Balloon Pump in VA-ECMO Patients: Insights from the Chinese Extracorporeal Life Support Registry

This study from the Chinese Extracorporeal Life Support (CSECLS) registry explored the effectiveness of using an intra-aortic balloon pump (IABP) alongside venoarterial extracorporeal membrane oxygenation (VA-ECMO) in patients undergoing treatment for refractory cardiogenic shock or cardiac arrest. Covering data from over 112 member centers, the study analyzed outcomes of 4,755 patients, comparing those who received VA-ECMO with IABP to those who did not. Findings indicated no significant difference in in-hospital mortality rates between the two groups, though IABP use was associated with higher incidences of continuous renal replacement therapy (CRRT) and limb ischemia. These results suggest that while IABP use does not reduce mortality in VA-ECMO patients, it may lead to increased complications, calling for further research and careful clinical decision-making.

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Cerebral P

Cerebral Protection in Acute Type A Aortic Dissection Surgery: A Comprehensive Systematic Review and Meta-Analysis

This systematic review and meta-analysis aimed to compare antegrade cerebral perfusion (ACP) and retrograde cerebral perfusion (RCP) methods for reducing cerebrovascular events during acute type A aortic dissection (ATAAD) surgeries. After assessing 26 studies involving 13,039 patients, findings suggest both ACP and RCP are safe and acceptable for emergency use. While no significant differences in permanent neurological dysfunction (PND) and mortality were observed between unilateral ACP (uACP) and bilateral ACP (bACP), uACP showed a preference in reducing transient neurologic deficits (TND). This study underscores the effectiveness of cerebral perfusion techniques in ATAAD surgery, highlighting uACP as a preferable method for minimizing TND.

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