International Perfusion Association

Day: February 7, 2024

AVR

The Northern New England Rapid Deployment Valve Experience: Survival and Procedural Outcomes From 2015 to 2021

This study examines the outcomes of rapid deployment aortic valve replacement (rdAVR) compared to stented aortic valve replacement (sAVR) in patients undergoing isolated aortic valve replacement or combined procedures with coronary artery bypass grafting from 2015 to 2021. Utilizing data from the Northern New England Cardiovascular Database, the research found that rdAVR offers significant advantages in terms of shorter cross-clamp and cardiopulmonary bypass times without compromising immediate postoperative gradients or long-term survival. However, rdAVR is associated with higher pacemaker rates, especially in larger valve sizes. The study concludes that rdAVR is a viable and safe alternative to sAVR, necessitating further long-term follow-up.

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Del Nido

Del Nido vs. Cold Blood Cardioplegia for High-Risk Isolated Coronary Artery Bypass Grafting in Patients with Reduced Ventricular Function

This study compares the effectiveness of del Nido and cold blood cardioplegia in high-risk patients with reduced ejection fraction undergoing isolated coronary artery bypass grafting. With 45 patient pairs matched for several factors, the research found that del Nido cardioplegia resulted in a higher rate of spontaneous return to sinus rhythm post-surgery and showed a trend towards lower creatine kinase release and atrial fibrillation rates, though mortality and major adverse cardiac events were similar between the two groups. The findings suggest del Nido cardioplegia may offer satisfactory myocardial protection in this patient demographic, highlighting the need for further prospective trials.

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Heart Art

Utility of Heparin-Binding Protein Following Cardiothoracic Surgery Using Cardiopulmonary Bypass

This research evaluates Heparin-Binding Protein (HBP) as a biomarker for detecting postoperative infection in patients undergoing cardiothoracic surgery with cardiopulmonary bypass (CPB). It found that HBP levels, which normalize quickly post-surgery, may indicate early postoperative sepsis. Analyzing 1475 patients, the study identified factors influencing HBP levels and its association with 30-day mortality, suggesting HBP’s potential in improving post-surgical outcomes by enabling timely infection detection.

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