International Perfusion Association

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IPA

Day: February 5, 2024

Mechanical Support

Mechanical Circulatory Support – Primer for Consultant Specialists

This article serves as a primer on mechanical life support therapies, focusing on nonrenal extracorporeal life support for cardiac and pulmonary functions. It targets nephrologist consultants involved in treating critically ill patients, often facing acute renal injury from cardiopulmonary shock and mechanical circulatory support. The review underscores the importance of these life-sustaining tools in managing organ failure, either as a bridge to recovery or as a gateway to more permanent mechanical support solutions.

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February 5, 2024
Pump Head

Target Flow Deviations on the Cardiopulmonary Bypass Cause Postoperative Delirium in Cardiothoracic Surgery – A Retrospective Study Evaluating Temporal Fluctuations of Perfusion Data

This study investigates the role of cardiopulmonary bypass (CPB) in postoperative delirium following cardiac surgery, employing algorithm-based data analysis on patient records from 2014 to 2019. It identifies not only demographic and comorbidity predictors but also highlights the significance of CPB parameters in delirium risk. Specifically, total blood volume and minimal blood flow rates during CPB were linked to delirium outcomes. The findings suggest that meticulous management of CPB parameters, especially flow rates and acid-base balance, could mitigate the risk of postoperative delirium, emphasizing the potential of precise CPB data processing in improving post-surgical care.

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February 5, 2024
Blood CPB

Protamine Dosing and Its Impact in Cardiac Surgery Transfusion Practice: A Retrospective Bi-institutional Analysis

This study investigates the correlation between protamine dosing and transfusion requirements in cardiac surgery, analyzing data from 762 patients who underwent cardiopulmonary bypass (CPB)-assisted cardiac surgery across two institutions. Patients were categorized into low-ratio (Protamine: UFH ≤ 0.8) and high-ratio (Protamine: UFH > 0.8) groups, based on the amount of protamine used to neutralize unfractionated heparin. Results indicated a significant increase in blood transfusion requirements in the high-ratio group, encompassing red blood cells, plasma, platelets, and cryoprecipitate, highlighting the need for precise protamine dosing to reduce bleeding and transfusion rates post-surgery.

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February 5, 2024

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