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The Anti-Apoptotic Effect of Ranolazine on Cerebral Protection during Cardiopulmonary Bypass and Carotid Artery Surgery
This study investigated the neuroprotective effects of ranolazine (Rn) in a rat model of cerebral ischemia induced by carotid artery clamping. Results showed that Rn-treated groups had significant changes in various biochemical markers, indicating an antiapoptotic effect of Rn in brain ischemia-reperfusion, suggesting its potential usability in cardiac surgeries and carotid artery interventions.