International Perfusion Association

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IPA

Day: January 25, 2024

The Rat

The Anti-Apoptotic Effect of Ranolazine on Cerebral Protection during Cardiopulmonary Bypass and Carotid Artery Surgery

This study investigated the neuroprotective effects of ranolazine (Rn) in a rat model of cerebral ischemia induced by carotid artery clamping. Results showed that Rn-treated groups had significant changes in various biochemical markers, indicating an antiapoptotic effect of Rn in brain ischemia-reperfusion, suggesting its potential usability in cardiac surgeries and carotid artery interventions.

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January 25, 2024
Mohamed Mohamed

GPT Serum CIRP Increases the Risk of Acute Kidney Injury After Cardiac Surgery

This study explored the connection between elevated Cold-induced RNA-binding protein (CIRP) levels and the incidence of acute kidney injury (AKI) following cardiac surgery, focusing on surgeries involving cardiopulmonary bypass (CPB). It was discovered that higher CIRP levels, especially in surgeries with CPB, are independently associated with a higher risk of developing AKI, leading to worse postoperative outcomes, including a lower survival rate over two years.

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January 25, 2024
PMP Membrane

Outcomes of ECMO Support with Polypropylene Membrane During Pandemic Times: A Retrospective Cohort Study

During the SARS-CoV-2 pandemic, a study compared clinical outcomes of patients on ECMO support using polypropylene (PP) oxygenation membranes versus poly-methylpentene (PMP) membranes. It found that PP membranes required more changes and had a higher frequency of renal replacement therapy as a complication, yet were a feasible alternative during supply shortages, without significant differences in mortality.

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January 25, 2024

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