Extracorporeal Membrane Oxygenation for Pulmonary Embolism: A Systematic Review and Meta-Analysis
This systematic review and meta-analysis of 39 studies involving 6409 patients reveal that more than 50% of patients with high-risk pulmonary embolism (HRPE) treated with extracorporeal membrane oxygenation (ECMO) survive, with mortality significantly lower in those receiving ECMO combined with catheter-directed therapy compared to systemic thrombolysis. Factors like cardiac arrest prior to ECMO and pre-ECMO heart rate are associated with mortality, highlighting the need for further research to compare ECMO with non-ECMO therapies.