International Perfusion Association

Day: January 15, 2024

Pulmonary Embolism

Extracorporeal Membrane Oxygenation for Pulmonary Embolism: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis of 39 studies involving 6409 patients reveal that more than 50% of patients with high-risk pulmonary embolism (HRPE) treated with extracorporeal membrane oxygenation (ECMO) survive, with mortality significantly lower in those receiving ECMO combined with catheter-directed therapy compared to systemic thrombolysis. Factors like cardiac arrest prior to ECMO and pre-ECMO heart rate are associated with mortality, highlighting the need for further research to compare ECMO with non-ECMO therapies.

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Redo Aorta

Redo Aortic Surgery: Does One Versus Multiple Affect Outcomes?

This study compares outcomes in patients undergoing redo aortic surgery after one versus multiple previous cardiac operations, finding that multiple redo surgeries are associated with higher short-term mortality and morbidity but similar long-term survival compared to first redo surgeries. Despite similar rates of postoperative complications, multiple redo surgeries have longer cardiopulmonary bypass and crossclamp times, and a higher incidence of dialysis.

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ECMO Ethics

Clinician Ethical Perspectives on Extracorporeal Membrane Oxygenation in Practice

This study surveys clinicians across seven U.S. hospitals to understand the informed consent process for Extracorporeal Membrane Oxygenation (ECMO) and ethical complexities in its application. Results reveal variability in the time spent on obtaining consent, use of exclusion criteria for ECMO, and differences in approaches to withdrawing ECMO, highlighting significant ethical challenges and inconsistencies in practice.

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