International Perfusion Association

Day: January 3, 2024

Florida State Surgeon General Calls for Halt in the Use of COVID-19 mRNA Vaccines

On December 6, 2023, Florida State Surgeon General Dr. Joseph A. Ladapo raised concerns to the FDA and CDC about potential nucleic acid contaminants in Pfizer and Moderna’s COVID-19 mRNA vaccines, specifically questioning the safety assessments regarding DNA integration risks. Despite FDA’s prior guidelines on DNA vaccines, Dr. Ladapo highlighted the lack of evidence for DNA integration assessments in these vaccines, emphasizing the unique health risks and advocating for non-mRNA COVID-19 vaccines and treatments.

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Thinking Virus

Divergent Attitudes Toward COVID-19 Vaccine vs Influenza Vaccine

This study explores attitudes toward COVID-19 and influenza vaccines among US adults. The data comes from a July 2023 survey of 1430 US adults, weighted for national representation. Results indicate similar perceptions of effectiveness for both vaccines, but diverging views on safety, with influenza vaccines seen as safer. Intentions to vaccinate also differed, with higher likelihood for influenza vaccination. Major reasons for hesitancy varied, with COVID-19 vaccine hesitancy often linked to distrust in government agencies and vaccine makers, and desire for more research. The study highlights the need for nuanced public health messaging to address these specific concerns and promote vaccine uptake.

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Chip Heart

Validation of an Automated Artificial Intelligence System for 12‑Lead ECG Interpretation

This study evaluates an AI-powered electrocardiogram (ECG) system with six deep neural networks (DNNs), trained to detect 20 diagnostic patterns in standard 12-lead ECGs, and compares its performance to current computerized interpretation methods. The results show that the AI system outperformed or matched state-of-the-art computerized ECG interpretation in all diagnostic categories, demonstrating its potential as a reliable clinical tool for detecting electrocardiographic abnormalities.

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Blood Clot

Early Blood Clot Detection Using Forward Scattering Light Measurements Is Not Superior to Delta Pressure Measurements

This study investigates the use of forward scattered light (FSL) measurements for early blood clot detection in extracorporeal membrane oxygenators, a method potentially superior to the current standard of monitoring pressure differences (ΔP) which fails to detect smaller, early-stage clots. Despite several modifications, FSL measurements were unable to reliably detect clots in an in vitro test circuit, whereas the current clinical gold standard of pressure measurements successfully detected fulminant clot formation in multiple experiments.

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